Equipoise：考虑参与高压氧治疗坏死性软组织感染随机对照试验时的重要伦理考虑因素。

IF 0.8 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Diving and hyperbaric medicine Pub Date : 2024-03-31 DOI:10.28920/dhm54.1.57-60

Bridget Devaney

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引用次数: 0

摘要

一项关于研究高压氧治疗（HBOT）在坏死性软组织感染（NSTI）中的作用的大型多中心随机对照试验提案在当地和国际上引起了广泛的讨论，讨论的焦点是对于一个利益相关者已将高压氧治疗视为标准实践的中心来说，参与该试验是否符合道德规范。本文系统阐述了针对 HBOT 在 NSTI 中的作用的临床等效概念，并提出了潜在参与机构的主要利益相关者应考虑的一系列因素。

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Equipoise: an important ethical consideration when contemplating participation in a randomised controlled trial of hyperbaric oxygen treatment in necrotising soft tissue infections.

A proposal for a large, multi-centre, randomised controlled trial investigating the role of hyperbaric oxygen treatment (HBOT) in necrotising soft tissue infections (NSTI) has led to much discussion locally and internationally about whether participation is ethical for a centre where stakeholders already consider HBOT standard practice. This article systematically addresses the concept of clinical equipoise specific to the role of HBOT in NSTI, and presents a series of considerations to be taken into account by key stakeholders at potential participating sites.

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来源期刊

Diving and hyperbaric medicine 医学-公共卫生、环境卫生与职业卫生

CiteScore

1.70

自引率

22.20%

发文量

审稿时长

>12 weeks

期刊介绍： Diving and Hyperbaric Medicine (DHM) is the combined journal of the South Pacific Underwater Medicine Society (SPUMS) and the European Underwater and Baromedical Society (EUBS). It seeks to publish papers of high quality on all aspects of diving and hyperbaric medicine of interest to diving medical professionals, physicians of all specialties, scientists, members of the diving and hyperbaric industries, and divers. Manuscripts must be offered exclusively to Diving and Hyperbaric Medicine, unless clearly authenticated copyright exemption accompaniesthe manuscript. All manuscripts will be subject to peer review. Accepted contributions will also be subject to editing.