Leonard C Steg, Ellen Jaspers, Anar Alshanbayeva, Rodrigo G Arzate-Meija, Maria A Dimitriu, Katharina Gapp, Lola M Kourouma, Kerem Uzel, Isabelle M Mansuy
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引用次数: 0
摘要
在过去的几十年里,后天性状可以跨代传递的可能性一直是人们热衷研究的课题。这一生物学过程引起了许多科学家的浓厚兴趣,并对生物学和社会产生了深远影响,但其机制复杂,因此研究难度很大。由于它涉及独立于 DNA 序列之外的因素,这种形式的遗传通常被称为表观遗传。许多研究都探讨了生活经历和各种环境因素如何导致表型遗传并在后代中表现出来。认识到这一研究的重要性和复杂性,第四届苏黎世表观遗传研讨会汇聚了来自不同学科的专家,探讨表观遗传领域的当前问题并介绍最新研究成果。研讨会专门讨论了流行病学证据和动物模型、传播机制、方法论以及对社会和进化的深远影响。本报告总结了发言者的发言,并介绍了研讨会期间开展的其他活动,包括以表观遗传为主题的海报展示和艺术竞赛。
Symposium summary: epigenetic inheritance-impact for biology and society 23-25 August 2023, Zürich, Switzerland.
The possibility that acquired traits can be transmitted across generations has been the subject of intense research in the past decades. This biological process is of major interest to many scientists and has profound implications for biology and society but has complex mechanisms and is therefore challenging to study. Because it involves factors independent from the DNA sequence, this form of heredity is classically referred to as epigenetic inheritance. Many studies have examined how life experiences and various environmental factors can cause phenotypes that are heritable and be manifested in subsequent generations. Recognizing the major importance and complexity of this research, the fourth edition of the Epigenetic Inheritance Symposium Zürich brought together experts from diverse disciplines to address current questions in the field of epigenetic inheritance and present recent findings. The symposium had sessions dedicated to epidemiological evidence and animal models, transmission mechanisms, methodologies and the far-reaching impact on society and evolution. This report summarizes the talks of speakers and describes additional activities offered during the symposium including poster sessions and an art competition on the topic of epigenetic inheritance.