结合灰阶超声波和多普勒诊断工具与应变弹性成像技术评估儿科炎症性肠病。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Ultrasound Pub Date : 2024-09-01 Epub Date: 2024-03-14 DOI:10.1007/s40477-024-00870-3
Enas Mamdooh Awad Allah Mohamed, Ayman Emil Eskander, Reham Osama Mahmoud, Hadeel Mohamed Seif Eldin Ali
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引用次数: 0

摘要

背景:炎症性肠病(IBD)的肠道变化经常通过超声波观察到。为了区分 IBD 的主要类型和检测并发症,通常会采用侵入性诊断程序。超声应变弹性成像(SE)是一种很有前途的非侵入性技术,可用于检测肠道变化和评估小儿 IBD 的炎症活动:本研究旨在评估传统超声波、彩色多普勒和SE在评估小儿炎症性肠病方面的诊断性能,既可单独使用,也可作为附加工具联合使用:40名通过临床和内镜活检初步诊断为 IBD 的患者(18 名女性和 22 名男性)以及 20 名健康对照者接受了常规超声波、彩色多普勒、SE 和实验室评估,包括全血细胞计数、血沉、CRP、粪便热保护蛋白以及使用 PIBDAI 评估 IBD 活动性:结果:传统超声波、彩色多普勒和SE对检测IBD的疾病活动性和肠道变化有明显作用(P 结论:传统超声波、彩色多普勒和SE对检测IBD的疾病活动性和肠道变化有明显作用:在灰阶超声波的基础上增加彩色多普勒和 SE 参数,在检测 IBD 的炎症活动和肠道变化方面具有与内窥镜、组织病理学和实验室标记相媲美的诊断价值。这种联合方法有助于避免不必要的侵入性随访技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Combined gray scale ultrasonography and doppler diagnostic tools with strain elastography in assessment of inflammatory bowel disease in pediatrics patients.

Background: Intestinal changes in inflammatory bowel disease (IBD) are frequently observed on ultrasound. Invasive diagnostic procedures are often employed to differentiate between the main types of IBD and detect complications. Ultrasound Strain Elastography (SE) is a promising non-invasive technique for detecting intestinal changes and assessing inflammatory activity in pediatric IBD.

Aim of the study: This research aims to evaluate the diagnostic performance of conventional ultrasound, color Doppler, and SE in assessing inflammatory bowel disease in pediatric patients, both separately and in combination as additional tools.

Patients and methods: Forty patients (18 females and 22 males) initially diagnosed with IBD through clinical and endoscopic biopsy, along with 20 healthy controls, underwent conventional ultrasound, color Doppler, SE, and laboratory evaluations, including CBC, ESR, CRP, Fecal calprotectin, and assessment of IBD activity using PIBDAI.

Results: Conventional ultrasound, color Doppler, and SE significantly contributed to detecting disease activity and intestinal changes in IBD (p < 0.001; 95% CI 0.79-1.100), demonstrating better sensitivity in combination compared to each method individually. The combined approach showed 100% sensitivity, 84% specificity, 78.6% precision (Positive Predictive Value), 100% Negative Predictive Value, and an overall accuracy of 92%.

Conclusion: The addition of Color Doppler and SE parameters to grayscale ultrasound provides diagnostic value comparable to endoscopy, histopathology, and laboratory markers in detecting inflammatory activity and intestinal changes in IBD. This combined approach can help avoid unnecessary invasive techniques for follow-up.

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来源期刊
Journal of Ultrasound
Journal of Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
4.10
自引率
15.00%
发文量
133
期刊介绍: The Journal of Ultrasound is the official journal of the Italian Society for Ultrasound in Medicine and Biology (SIUMB). The journal publishes original contributions (research and review articles, case reports, technical reports and letters to the editor) on significant advances in clinical diagnostic, interventional and therapeutic applications, clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and in cross-sectional diagnostic imaging. The official language of Journal of Ultrasound is English.
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