能否利用临床和远程医疗数据估算出重症监护室和普通病房收治的 COVID-19 患者人数?

IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL
Einstein-Sao Paulo Pub Date : 2024-03-08 eCollection Date: 2024-01-01 DOI:10.31744/einstein_journal/2024AO0328
Caio Querino Gabaldi, Adriana Serra Cypriano, Carlos Henrique Sartorato Pedrotti, Daniel Tavares Malheiro, Claudia Regina Laselva, Miguel Cendoroglo Neto, Vanessa Damazio Teich
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引用次数: 0

摘要

背景Gabaldi 等人利用远程医疗数据、网络搜索趋势、住院病人特征和资源使用数据来估计 COVID-19 大流行期间的病床占用率。研究结果展示了数据驱动策略在加强资源分配决策以有效应对大流行病方面的潜力:开发并验证预测模型,以估算在巴西圣保罗一家非营利性私立医院重症监护室和普通病房住院的 COVID-19 患者人数:开发了两个主要模型。第一个模型将 COVID-19 患者入院、科室间转院和出院预测值之间的差值作为医院占用率进行计算,根据每周移动平均值估算入院人数,并按普通病房和重症监护病房进行细分。患者出院预测以住院时间预测模型为基础,评估 COVID-19 住院患者的临床特征,包括年龄组和机械通气设备的使用情况。第二个模型根据确诊为 COVID-19 的患者远程医疗就诊次数的相关性来估算住院时间,利用相关性分析来确定最大化研究序列之间相关性的滞后期。从 2021 年 5 月 20 日到 2022 年 5 月 20 日,对这两个模型进行了为期 365 天的监测:第一个模型预测了14天内各科室住院病人的数量。第二个模型考虑到以色列阿尔伯特-爱因斯坦医院远程医疗部门接听的电话,估算出随后 8 天的住院病人总数。考虑到重症监护室和普通病房在第二个模型限定的 8 天预测范围内的日平均预测值,第一个和第二个模型的 R² 值分别为 0.900 和 0.996,平均绝对误差分别为 8.885 和 2.524 个床位。利用平均误差、平均绝对误差和均方根误差作为预测天数的函数,对两个模型的性能进行了监测:在本次分析中,基于远程医疗使用情况的模型最为准确,可用于提前 8 天估算 COVID-19 的医院占用率,在类似的临床环境中验证了这种性质的预测。研究结果鼓励将这一方法推广到其他病症中,以保证医院护理的标准并有意识地消耗资源:开发了长达 14 天的病床占用率预测模型,并对误差进行了 365 天的监测:COVID-19患者的远程医疗呼叫与未来8天住院患者人数相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is it possible to estimate the number of patients with COVID-19 admitted to intensive care units and general wards using clinical and telemedicine data?

Background: Gabaldi et al. utilized telemedicine data, web search trends, hospitalized patient characteristics, and resource usage data to estimate bed occupancy during the COVID-19 pandemic. The results showcase the potential of data-driven strategies to enhance resource allocation decisions for an effective pandemic response.

Objective: To develop and validate predictive models to estimate the number of COVID-19 patients hospitalized in the intensive care units and general wards of a private not-for-profit hospital in São Paulo, Brazil.

Methods: Two main models were developed. The first model calculated hospital occupation as the difference between predicted COVID-19 patient admissions, transfers between departments, and discharges, estimating admissions based on their weekly moving averages, segmented by general wards and intensive care units. Patient discharge predictions were based on a length of stay predictive model, assessing the clinical characteristics of patients hospitalized with COVID-19, including age group and usage of mechanical ventilation devices. The second model estimated hospital occupation based on the correlation with the number of telemedicine visits by patients diagnosed with COVID-19, utilizing correlational analysis to define the lag that maximized the correlation between the studied series. Both models were monitored for 365 days, from May 20th, 2021, to May 20th, 2022.

Results: The first model predicted the number of hospitalized patients by department within an interval of up to 14 days. The second model estimated the total number of hospitalized patients for the following 8 days, considering calls attended by Hospital Israelita Albert Einstein's telemedicine department. Considering the average daily predicted values for the intensive care unit and general ward across a forecast horizon of 8 days, as limited by the second model, the first and second models obtained R² values of 0.900 and 0.996, respectively and mean absolute errors of 8.885 and 2.524 beds, respectively. The performances of both models were monitored using the mean error, mean absolute error, and root mean squared error as a function of the forecast horizon in days.

Conclusion: The model based on telemedicine use was the most accurate in the current analysis and was used to estimate COVID-19 hospital occupancy 8 days in advance, validating predictions of this nature in similar clinical contexts. The results encourage the expansion of this method to other pathologies, aiming to guarantee the standards of hospital care and conscious consumption of resources.

Background: Developed models to forecast bed occupancy for up to 14 days and monitored errors for 365 days.

Background: Telemedicine calls from COVID-19 patients correlated with the number of patients hospitalized in the next 8 days.

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Einstein-Sao Paulo
Einstein-Sao Paulo MEDICINE, GENERAL & INTERNAL-
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210
审稿时长
38 weeks
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