卵巢周围脂肪组织--对卵巢功能的影响。

IF 1.9 4区 医学 Q3 PHYSIOLOGY
W Szyrzisko, M Grzesiak
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引用次数: 0

摘要

卵巢周围脂肪组织(POAT)是一种环绕卵巢的性腺白色脂肪组织。卵巢周围脂肪组织是各种生物活性分子的来源,如脂肪因子、细胞因子、趋化因子、生长因子和激素。因此,它可以影响卵巢的重要功能。最近的研究结果表明,切除 POAT 会影响卵巢的卵泡生成和类固醇生成。此外,还观察到更年期或多囊卵巢综合症妇女的 POAT 形态和功能发生了变化。虽然身体能量状态与女性生育力之间的关系已广为人知,但 POAT 的作用仍难以捉摸。因此,本综述旨在总结有关 POAT 在卵巢生理和病理过程中功能的实际知识状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Periovarian Adipose Tissue - an Impact on Ovarian Functions.

Periovarian adipose tissue (POAT) is a type of gonadal white adipose tissue that surrounds the ovary. POAT is a source of various bioactive molecules, such as adipokines, cytokines, chemokines, growth factors and hormones. Thereby it could influence crucial ovarian functions. Recent findings showed that removal of POAT affects folliculogenesis and steroidogenesis in the ovary. Furthermore, changes in the morphology and function of POAT were observed in women during menopause or polycystic ovary syndrome. Although the relationship between the body's energy status and fertility in females is generally well known, the contribution of POAT remains still elusive. Therefore, the objective of this review is summarizing the actual state of knowledge about POAT function in physiological and pathological processes within the ovary.

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来源期刊
Physiological research
Physiological research 医学-生理学
CiteScore
4.00
自引率
4.80%
发文量
108
审稿时长
3 months
期刊介绍: Physiological Research is a peer reviewed Open Access journal that publishes articles on normal and pathological physiology, biochemistry, biophysics, and pharmacology. Authors can submit original, previously unpublished research articles, review articles, rapid or short communications. Instructions for Authors - Respect the instructions carefully when submitting your manuscript. Submitted manuscripts or revised manuscripts that do not follow these Instructions will not be included into the peer-review process. The articles are available in full versions as pdf files beginning with volume 40, 1991. The journal publishes the online Ahead of Print /Pre-Press version of the articles that are searchable in Medline and can be cited.
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