脂肪垫和滑膜中的 APOE 是导致膝关节 OA 的原因之一。

IF 29.4 1区医学 Q1 RHEUMATOLOGY

Nature Reviews Rheumatology Pub Date : 2024-03-07 DOI:10.1038/s41584-024-01099-4

Robert Phillips

引用次数: 0

摘要

新研究发现，髌下脂肪垫和滑膜中的成纤维细胞和巨噬细胞表达的载脂蛋白E是膝骨关节炎的致病介质和潜在治疗靶点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

APOE in fat pad and synovium contributes to knee OA

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APOE in fat pad and synovium contributes to knee OA

New research has identified apolipoprotein E expressed by fibroblasts and macrophages in the infrapatellar fat pad and synovium as a pathogenetic mediator and potential therapeutic target in knee osteoarthritis.

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来源期刊

Nature Reviews Rheumatology 医学-风湿病学

CiteScore

29.90

自引率

0.90%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.