{"title":"脑岛的神经发育结构病变是精神分裂症风险的潜在生物标志物吗?","authors":"Susanna Gebhardt, Henry A. Nasrallah","doi":"10.1016/j.bionps.2024.100086","DOIUrl":null,"url":null,"abstract":"<div><p>The insula is a significant neural region associated with the development and clinical symptoms of schizophrenia. Here, we provide an overview of the role of the insula in a non-pathological context, as well as its function in schizophrenia, discussing how structural and functional changes to the insula can provide insight into the etiology of schizophrenia and contribute to potential therapeutic intervention.</p></div>","PeriodicalId":52767,"journal":{"name":"Biomarkers in Neuropsychiatry","volume":"10 ","pages":"Article 100086"},"PeriodicalIF":0.0000,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666144624000042/pdfft?md5=78ea40cb67d1ec6d2ba22b33ab8ab1a0&pid=1-s2.0-S2666144624000042-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?\",\"authors\":\"Susanna Gebhardt, Henry A. Nasrallah\",\"doi\":\"10.1016/j.bionps.2024.100086\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The insula is a significant neural region associated with the development and clinical symptoms of schizophrenia. Here, we provide an overview of the role of the insula in a non-pathological context, as well as its function in schizophrenia, discussing how structural and functional changes to the insula can provide insight into the etiology of schizophrenia and contribute to potential therapeutic intervention.</p></div>\",\"PeriodicalId\":52767,\"journal\":{\"name\":\"Biomarkers in Neuropsychiatry\",\"volume\":\"10 \",\"pages\":\"Article 100086\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666144624000042/pdfft?md5=78ea40cb67d1ec6d2ba22b33ab8ab1a0&pid=1-s2.0-S2666144624000042-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomarkers in Neuropsychiatry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666144624000042\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomarkers in Neuropsychiatry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666144624000042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
The insula is a significant neural region associated with the development and clinical symptoms of schizophrenia. Here, we provide an overview of the role of the insula in a non-pathological context, as well as its function in schizophrenia, discussing how structural and functional changes to the insula can provide insight into the etiology of schizophrenia and contribute to potential therapeutic intervention.