评估 Er,Cr:YSGG激光在非手术治疗种植体周围炎中对种植体周围缝隙液中核因子卡巴B配体受体激活剂和骨保护素水平的影响:随机临床试验。

IF 4.2 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Nazli Zeynep Alpaslan, Dicle Altindal, Damla Akbal, Ahmet Cemil Talmac, Serap Keskin Tunc, Abdullah Seckin Ertugrul
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引用次数: 0

摘要

背景:本研究旨在探讨铒、铬掺杂:钇、钪、镓、石榴石(Er,Cr:YSGG)激光联合非手术机械清创(MD)治疗种植体周围炎对临床参数和种植体周围缝隙液核因子卡巴B配体受体激活剂(RANKL)和骨保护素(OPG)水平的影响:方法:将49名接受非手术治疗的种植体周围炎患者随机分为两组。对照组(26 人)仅接受 MD 治疗,激光组(23 人)接受 MD+Er,Cr:YSGG 治疗。分别在基线(T0)和治疗后 6 个月(T1)测量临床参数(探诊出血[BoP]、牙龈指数[GI]、牙菌斑指数[PI]、探诊深度[PD])、边缘骨质流失(MBL)和生化参数(RANKL 和 OPG):结果:与 T0 相比,两组患者在 T1 时的所有临床参数均有统计学意义上的显著下降(p 结论:虽然两种治疗方法对治疗骨质疏松症都有影响,但在 T1 和 T2 时的所有临床参数均有显著下降:虽然两种治疗方法对治疗种植体周围炎都有影响,但激光组(MD+Er,Cr:YSGG)通过减少临床炎症和改善生化指标取得了更有利的结果。基于这些研究结果,Er,Cr:YSGG 激光可能是这类患者的一种有益的辅助治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Evaluation of the effect of Er,Cr:YSGG laser application on peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand and osteoprotegerin levels in the non-surgical treatment of peri-implantitis: A randomized clinical trial

Evaluation of the effect of Er,Cr:YSGG laser application on peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand and osteoprotegerin levels in the non-surgical treatment of peri-implantitis: A randomized clinical trial

Background

This study aimed to investigate the effect of erbium, chromium doped:yttrium,scandium,gallium,garnet (Er,Cr:YSGG) laser application combined with non-surgical mechanical debridement (MD) on clinical parameters and peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) levels in the treatment of peri-implantitis.

Methods

A total of 49 patients who underwent non-surgical treatment of peri-implantitis were randomly divided into two groups. The control group (n = 26) received MD alone, while the laser group (n = 23) received MD+Er,Cr:YSGG. The clinical parameters (bleeding on probing [BoP], gingival index [GI], plaque index [PI], probing depth [PD]), marginal bone loss (MBL), and biochemical parameters (RANKL and OPG) were measured at baseline (T0) and 6 months after treatment (T1).

Results

There was a statistically significant decrease in all the clinical parameters in both groups at T1 compared to T0 (p < 0.05). The BoP, PD, MBL, and RANKL reductions were significantly higher in the laser group than in the control group (p = 0.046, p = 0.014, p = 0.047, p = 0.045, respectively). The OPG levels significantly increased at T1 in the laser group (p = 0.01). The OPG/RANKL ratio increased significantly in both groups at T1, which favored the laser group (p = 0.034).

Conclusions

Although both treatment methods were influential in treating peri-implantitis, the laser group (MD+Er,Cr:YSGG) yielded more favorable results by reducing clinical inflammation and improving biochemical parameters. Based on these findings, Er,Cr:YSGG laser may be a beneficial adjunctive treatment in this patient group.

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来源期刊
Journal of periodontology
Journal of periodontology 医学-牙科与口腔外科
CiteScore
9.10
自引率
7.00%
发文量
290
审稿时长
3-8 weeks
期刊介绍: The Journal of Periodontology publishes articles relevant to the science and practice of periodontics and related areas.
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