{"title":"ATP-γ- s(腺苷5′- o -(3-硫代三磷酸))微注射可提高爪蟾卵母细胞孕激素刺激组蛋白激酶活性","authors":"J.C. Labbé , A. Picard , M. Dorée","doi":"10.1016/0045-6039(88)90072-3","DOIUrl":null,"url":null,"abstract":"<div><p>Progesterone stimulates the activity of a potent Ca<sup>2+</sup>- and cyclic nucleotide-independent histone kinase in <em>Xenopus</em> oocytes. Microinjection of ATP-γ-S during the course of meiotic maturation or after the oocytes had arrested at second meiotic metaphase resulted in a further increase of this histone kinase activity in progesterone-stimulated oocytes. ATP-γ-S microinjection also increased and stabilized the activity of the maturation-promoting factor. The possible mechanism of ATP-γ-S action is discussed.</p></div>","PeriodicalId":75684,"journal":{"name":"Cell differentiation","volume":"23 3","pages":"Pages 201-206"},"PeriodicalIF":0.0000,"publicationDate":"1988-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0045-6039(88)90072-3","citationCount":"2","resultStr":"{\"title\":\"ATP-γ-S (adenosine 5′-O-(3-thiotriphosphate)) microinjection increases progesterone-stimulated histone kinase activity in Xenopus oocytes\",\"authors\":\"J.C. Labbé , A. Picard , M. Dorée\",\"doi\":\"10.1016/0045-6039(88)90072-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Progesterone stimulates the activity of a potent Ca<sup>2+</sup>- and cyclic nucleotide-independent histone kinase in <em>Xenopus</em> oocytes. Microinjection of ATP-γ-S during the course of meiotic maturation or after the oocytes had arrested at second meiotic metaphase resulted in a further increase of this histone kinase activity in progesterone-stimulated oocytes. ATP-γ-S microinjection also increased and stabilized the activity of the maturation-promoting factor. The possible mechanism of ATP-γ-S action is discussed.</p></div>\",\"PeriodicalId\":75684,\"journal\":{\"name\":\"Cell differentiation\",\"volume\":\"23 3\",\"pages\":\"Pages 201-206\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0045-6039(88)90072-3\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell differentiation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0045603988900723\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell differentiation","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0045603988900723","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Progesterone stimulates the activity of a potent Ca2+- and cyclic nucleotide-independent histone kinase in Xenopus oocytes. Microinjection of ATP-γ-S during the course of meiotic maturation or after the oocytes had arrested at second meiotic metaphase resulted in a further increase of this histone kinase activity in progesterone-stimulated oocytes. ATP-γ-S microinjection also increased and stabilized the activity of the maturation-promoting factor. The possible mechanism of ATP-γ-S action is discussed.
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