中等恶性程度的血管肿瘤：最新进展。

IF 2.7 2区医学 Q2 PATHOLOGY

Human pathology Pub Date : 2024-05-01 DOI:10.1016/j.humpath.2024.01.014

Andrew L. Folpe

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引用次数: 0

摘要

血管内皮瘤 "一词用于指中等恶性程度的内皮肿瘤，描述了一组生物行为介于良性血管瘤和完全恶性血管肉瘤之间的罕见肿瘤。血管内皮细胞瘤分为几种特殊的、临床病理学和遗传学上不同的实体，具体包括上皮样血管内皮细胞瘤、卡波丝状血管内皮细胞瘤、乳头状淋巴内血管内皮细胞瘤和网状血管内皮细胞瘤（滚刀状血管内皮细胞瘤）、假肌生成性血管内皮细胞瘤、复合型血管内皮细胞瘤和 YAP1::TFE3 融合型血管内皮细胞瘤。本综述将讨论这些罕见实体的临床、形态、免疫组化和遗传特征以及鉴别诊断。

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Vascular tumors of intermediate malignancy: An update

The term “hemangioendothelioma” is used for endothelial neoplasms of intermediate malignancy and describes a group of rare neoplasms having biologic behavior falling in between that of the benign hemangiomas and fully malignant angiosarcomas. The hemangioendotheliomas fall into several specific, clinicopathologically and genetically distinct entities, specifically epithelioid hemangioendothelioma, kaposiform hemangioendothelioma, papillary intralymphatic angioendothelioma and retiform hemangioendothelioma (hobnailed hemangioendothelioma), pseudomyogenic hemangioendothelioma, composite hemangioendothelioma, and YAP1::TFE3-fused hemangioendothelioma. The clinical, morphologic, immunohistochemical, and genetic features, and the differential diagnosis of each of these rare entities are discussed in this review.

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来源期刊

Human pathology 医学-病理学

CiteScore

5.30

自引率

6.10%

发文量

206

审稿时长

21 days

期刊介绍： Human Pathology is designed to bring information of clinicopathologic significance to human disease to the laboratory and clinical physician. It presents information drawn from morphologic and clinical laboratory studies with direct relevance to the understanding of human diseases. Papers published concern morphologic and clinicopathologic observations, reviews of diseases, analyses of problems in pathology, significant collections of case material and advances in concepts or techniques of value in the analysis and diagnosis of disease. Theoretical and experimental pathology and molecular biology pertinent to human disease are included. This critical journal is well illustrated with exceptional reproductions of photomicrographs and microscopic anatomy.