Catherine Sykes, Matthew Banks, Humayra Dervin, Andres Vales, Rami Sweis
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引用次数: 0
摘要
一名 60 多岁的妇女因吞咽困难和胸痛被转诊到一家专门治疗食道疾病的三级转诊中心。她在苏格兰国家医疗服务体系的当地医院排除了心脏症状和食道病变的可能性。在多学科团队的监督下,对粘膜病理和食管运动的重新调查最终发现了 III 型贲门失弛缓症和嗜酸性粒细胞性食管炎。该病例表明,在高分辨率测压过程中进行挑衅性测试以重现相关吞咽困难是有好处的,而且停用质子泵抑制剂足够长的时间以发现过多的嗜酸性粒细胞也很重要,否则可能会被掩盖。最终,需要对这两种情况分别进行量身定制的治疗,才能使症状得到缓解。
A woman in her early 60s was referred with dysphagia and chest pain to a tertiary referral centre specialising in oesophageal disorders. Cardiac symptom origin and sinister oesophageal pathology had been excluded at her local hospital in NHS Scotland. Under multidisciplinary team oversight, reinvestigation of mucosal pathology and oesophageal motility ultimately uncovered both Type III achalasia and eosinophilic oesophagitis. This case demonstrates the benefit of including provocative testing during high-resolution manometry to reproduce relevant dysphagia and the importance of stopping proton-pump inhibitors long enough to uncover excessive eosinophils which could otherwise be masked. Ultimately, tailored management for both conditions separately was required to achieve symptoms resolution.
期刊介绍:
Clinical Medicine is aimed at practising physicians in the UK and overseas and has relevance to all those managing or working within the healthcare sector.
Available in print and online, the journal seeks to encourage high standards of medical care by promoting good clinical practice through original research, review and comment. The journal also includes a dedicated continuing medical education (CME) section in each issue. This presents the latest advances in a chosen specialty, with self-assessment questions at the end of each topic enabling CPD accreditation to be acquired.
ISSN: 1470-2118 E-ISSN: 1473-4893 Frequency: 6 issues per year