巴西南部高中生角膜炎患病率:一项基于社区的研究。

IF 2 4区 医学 Q2 OPHTHALMOLOGY
Otavio de Azevedo Magalhães, Bruna Nunes Pagano, Luana Veber Grellmann, Victor Sanchez Zago, Claudia Leite Kronbauer
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引用次数: 0

摘要

研究目的本研究旨在确定巴西南部青少年角膜病(KC)的发病率,并检测任何可能的相关因素:这项前瞻性、观察性、基于流动诊所的横断面研究收集了巴西南部大阿雷格里港大都会地区 7 所高中 14 至 21 岁学生的数据。受试者接受了临床调查,并使用裂隙灯和旋转式 Scheimpflug 角膜断层扫描系统进行了检查。所有数据都是在流动诊所的一次就诊中收集的:共有 826 名学生接受了评估(男生 357 人,女生 469 人),平均年龄为 16.7±1.2 岁。六名受试者被归类为 KC 患者(四名女生),患病率为 0.73%(95% 置信区间,0.27%-1.57%),即巴西南部每 137 名青少年中就有一人患病。逻辑回归显示,KC 与揉眼史之间存在关联(P=0.02):根据我们的调查,这是南美洲首次使用最新技术(Scheimpflug 成像)进行的 KC 患病率研究。巴西南部青少年的 KC 患病率属于全球报告的最高患病率之列。我们还发现 KC 与揉眼史之间存在关联。角膜塑形镜在我国人群中并不罕见,因此有必要尽早发现该疾病并减少其风险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Keratoconus Among High School Students in Southern Brazil: A Community-Based Study.

Objectives: This study aimed to determine the prevalence of keratoconus (KC) in teenagers who live in Southern Brazil and detect any possible associated factors.

Methods: This prospective, observational, mobile clinic-based cross-sectional study collected data from students between 14 and 21 years from seven high schools who were living in the Greater Porto Alegre metropolitan region in Southern Brazil. Subjects were clinically surveyed and examined using a slitlamp and rotational Scheimpflug corneal tomography system. All data were collected at the mobile clinic during a single visit.

Results: Eight-hundred twenty-six students were evaluated (357 boys and 469 girls) with an average age of 16.7±1.2 years. Six subjects were classified as having KC (four girls), yielding a prevalence rate of 0.73% (95% confidence interval, 0.27%-1.57%) or one per 137 teenagers in Southern Brazil. Logistic regression showed an association between KC and positive history of eye rubbing ( P =0.02).

Conclusion: According to our investigation, this is the first KC prevalence study in South America using the latest technologies (Scheimpflug imaging). The prevalence of KC among teenagers in Southern Brazil is within the highest reported worldwide. We also found an association between KC and history of eye rubbing. Keratoconus is not an uncommon disorder in our population, and the efforts to identify the disease and reduce its risk factors in an earlier phase are justified.

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来源期刊
CiteScore
4.50
自引率
4.30%
发文量
150
审稿时长
6-12 weeks
期刊介绍: Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.
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