[卡帕霉素——一种新的吡咯醚抗生素]。

N V Murenets, M K Kudinova, T P Korobkova, T N Drobysheva, N A Kliuev
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引用次数: 0

摘要

卡霉素是一种抗革兰氏阳性菌的新型聚醚类抗生素。它是从一种产生蒽环类抗生素加拉他霉素的生物链霉菌的培养液中分离出来的。采用紫外、PMR、质谱和CD等光谱分析方法鉴定了卡霉素的结构,并对其理化特性和生物学特性进行了描述。卡霉素被证明是一种类似于吲哚霉素(X-14547A)的吡咯醚类抗生素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Kafamycin--a new pyrrol ether antibiotic].

Cafamycin is a novel polyether antibiotic active against gram-positive bacteria. It was isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin. The structure of cafamycin was assessed by spectral analysis: UV, PMR, mass spectroscopy and CD. Physico-chemical and biological properties of the antibiotic are described. Cafamycin was shown to be an analog of indanomycin (X-14547A), a pyrrol ether antibiotic.

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