支架植入术后打鼾对颈动脉血流动力学的影响:振荡的作用。

IF 0.8 4区 医学 Q4 BIOPHYSICS
Xianghao Zhang, Zhenmin Fan, Xiao Liu, Mingyuan Liu, Xia Ye, Xiaoyan Deng
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引用次数: 0

摘要

在接受血管内支架治疗的超重和老年患者中,打鼾是常见现象。研究证明,打鼾与颈动脉狭窄之间存在相关性,因此,颈动脉支架植入术(CAS)后打鼾可能会促进或恶化临床表现。本研究通过构建患者特异性颈动脉分叉模型,并对不同打鼾条件下颈动脉的血流动力学变化进行数值分析,从而验证了这一假设。这些条件包括小振幅和大振幅、低频率和高频率以及不同年龄组。结果发现,高振幅打鼾抑制了支架段的紊乱血流,而颈内动脉下游区域则变得更加混乱,这是支架内膜再狭窄和血栓形成的原因。此外,有打鼾症状的老年人群的局部血流模式更容易因低速血流而发生改变,增加了血管重塑和血栓形成的可能性。此外,打鼾频率的增加几乎不会影响局部紊乱的血流。因此,老年人在接受高振幅打鼾支架术后应尽快积极接受治疗,以避免潜在的不良事件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hemodynamic impact of snoring on carotid artery after stent implantation: the role of oscillation.

Snoring is common in overweight and elderly patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. The results found that high amplitude snoring suppressed the disturbed flow at the stented segment while the downstream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Therefore, older adults should receive medical treatment actively after stenting for high-amplitude snoring as soon as possible to avoid potential adverse events.

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来源期刊
Acta of bioengineering and biomechanics
Acta of bioengineering and biomechanics BIOPHYSICS-ENGINEERING, BIOMEDICAL
CiteScore
2.10
自引率
10.00%
发文量
0
期刊介绍: Acta of Bioengineering and Biomechanics is a platform allowing presentation of investigations results, exchange of ideas and experiences among researchers with technical and medical background. Papers published in Acta of Bioengineering and Biomechanics may cover a wide range of topics in biomechanics, including, but not limited to: Tissue Biomechanics, Orthopedic Biomechanics, Biomaterials, Sport Biomechanics.
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