同种异体造血干细胞移植后的长期毒性:韩国一项基于人群的研究

IF 1.8 Q3 ONCOLOGY
J. Kwon, Byoung Hyuck Kim
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引用次数: 0

摘要

甲状腺功能减退(1.50;95% CI,1.1-2.1)在创伤性脑损伤后明显增加。不过,不同创伤性脑损伤导致的心肌梗死和中风的发生率没有明显差异。结论:我们的研究结果表明,现代创伤性脑损伤可能不会额外增加异基因造血干细胞移植后发生 SC 的风险,但其他疾病的风险有所增加。医生应仔细考虑 TBI 的个体化风险和益处,尤其要关注年龄组。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term toxicities after allogeneic hematopoietic stem cell transplantation with or without total body irradiation: a population-based study in Korea
hypo-thyroidism (1.50; 95% CI, 1.1–2.1) were significantly increased after TBI. However, there were no significant differences in the occurrence of myocardial infarction and stroke according to TBI. Conclusions: Our results suggest that modern TBI may not additionally increase the risk of SC after allogeneic HSCT, although increased risks of other diseases were noted. Physicians should carefully consider individualized risks and benefits of TBI, with a particular focus by age group.
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来源期刊
CiteScore
3.50
自引率
4.30%
发文量
24
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