美国北部一例皮肤利什曼病并发黏膜受累病例

IF 1.2 4区医学 Q3 EMERGENCY MEDICINE

Journal of Emergency Medicine Pub Date : 2024-06-01 DOI:10.1016/j.jemermed.2024.01.015

Timothy Graziano DO , Andrew J. Ferdock BS , Carla M. Rossi MD , Kristine L. Schultz MD

{"title":"美国北部一例皮肤利什曼病并发黏膜受累病例","authors":"Timothy Graziano DO , Andrew J. Ferdock BS , Carla M. Rossi MD , Kristine L. Schultz MD","doi":"10.1016/j.jemermed.2024.01.015","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Cutaneous leishmaniasis (CL) is a vector-borne parasitic infection endemic to many sub-tropical regions worldwide. In the Americas, <em>Leishmania braziliensis</em> is responsible for most reported CL cases. Variable symptom presentation and susceptibility to secondary infection make diagnosing CL a difficult proposition for physicians who may not encounter cases frequently.</p></div><div><h3>Case Report</h3><p>We present the case of a 50-year-old man with multiple progressive lesions, diagnosed initially as a bacterial infection, who presented to a North American emergency department after several unsuccessful trials of antibiotic therapy. Eventually, polymerase chain reaction testing of a wound biopsy sample confirmed the presence of <em>L. braziliensis</em>. After a complicated course, the patient's infection resolved after tailored antiparasitic therapy.</p></div><div><h3>Why Should an Emergency Physician Be Aware of This?</h3><p>This case highlights the need to include travel history in the evaluation of atypical dermatologic infections.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Case of Cutaneous Leishmaniasis with Mucosal Involvement in the Northern United States\",\"authors\":\"Timothy Graziano DO , Andrew J. Ferdock BS , Carla M. Rossi MD , Kristine L. Schultz MD\",\"doi\":\"10.1016/j.jemermed.2024.01.015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Cutaneous leishmaniasis (CL) is a vector-borne parasitic infection endemic to many sub-tropical regions worldwide. In the Americas, <em>Leishmania braziliensis</em> is responsible for most reported CL cases. Variable symptom presentation and susceptibility to secondary infection make diagnosing CL a difficult proposition for physicians who may not encounter cases frequently.</p></div><div><h3>Case Report</h3><p>We present the case of a 50-year-old man with multiple progressive lesions, diagnosed initially as a bacterial infection, who presented to a North American emergency department after several unsuccessful trials of antibiotic therapy. Eventually, polymerase chain reaction testing of a wound biopsy sample confirmed the presence of <em>L. braziliensis</em>. After a complicated course, the patient's infection resolved after tailored antiparasitic therapy.</p></div><div><h3>Why Should an Emergency Physician Be Aware of This?</h3><p>This case highlights the need to include travel history in the evaluation of atypical dermatologic infections.</p></div>\",\"PeriodicalId\":16085,\"journal\":{\"name\":\"Journal of Emergency Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Emergency Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0736467924000179\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"EMERGENCY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Emergency Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0736467924000179","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}

引用次数: 0

摘要

背景皮肤利什曼病（CL）是一种病媒传播的寄生虫病，在全球许多亚热带地区流行。在美洲，大多数报告的利什曼病病例都是由巴西利什曼病引起的。病例报告我们介绍了一例 50 岁男子的病例，他患有多发性进展性病变，最初被诊断为细菌感染，在多次抗生素治疗无效后，他来到北美的一家急诊科就诊。最终，伤口活检样本的聚合酶链反应（PCR）检测证实了巴西痢疾杆菌的存在。为什么急诊医生应该注意这一点？本病例强调了在评估非典型皮肤感染时纳入旅行史的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A Case of Cutaneous Leishmaniasis with Mucosal Involvement in the Northern United States

Background

Cutaneous leishmaniasis (CL) is a vector-borne parasitic infection endemic to many sub-tropical regions worldwide. In the Americas, Leishmania braziliensis is responsible for most reported CL cases. Variable symptom presentation and susceptibility to secondary infection make diagnosing CL a difficult proposition for physicians who may not encounter cases frequently.

Case Report

We present the case of a 50-year-old man with multiple progressive lesions, diagnosed initially as a bacterial infection, who presented to a North American emergency department after several unsuccessful trials of antibiotic therapy. Eventually, polymerase chain reaction testing of a wound biopsy sample confirmed the presence of L. braziliensis. After a complicated course, the patient's infection resolved after tailored antiparasitic therapy.

Why Should an Emergency Physician Be Aware of This?

This case highlights the need to include travel history in the evaluation of atypical dermatologic infections.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Emergency Medicine 医学-急救医学

CiteScore

2.40

自引率

6.70%

发文量

339

审稿时长

2-4 weeks

期刊介绍： The Journal of Emergency Medicine is an international, peer-reviewed publication featuring original contributions of interest to both the academic and practicing emergency physician. JEM, published monthly, contains research papers and clinical studies as well as articles focusing on the training of emergency physicians and on the practice of emergency medicine. The Journal features the following sections: • Original Contributions • Clinical Communications: Pediatric, Adult, OB/GYN • Selected Topics: Toxicology, Prehospital Care, The Difficult Airway, Aeromedical Emergencies, Disaster Medicine, Cardiology Commentary, Emergency Radiology, Critical Care, Sports Medicine, Wound Care • Techniques and Procedures • Technical Tips • Clinical Laboratory in Emergency Medicine • Pharmacology in Emergency Medicine • Case Presentations of the Harvard Emergency Medicine Residency • Visual Diagnosis in Emergency Medicine • Medical Classics • Emergency Forum • Editorial(s) • Letters to the Editor • Education • Administration of Emergency Medicine • International Emergency Medicine • Computers in Emergency Medicine • Violence: Recognition, Management, and Prevention • Ethics • Humanities and Medicine • American Academy of Emergency Medicine • AAEM Medical Student Forum • Book and Other Media Reviews • Calendar of Events • Abstracts • Trauma Reports • Ultrasound in Emergency Medicine