金属基纳米粒子的抗菌活性：微型综述。

IF 4.1 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biometals Pub Date : 2024-01-29 DOI:10.1007/s10534-023-00573-y

Marharyta Hancharova, Kinga Halicka-Stępień, Aleksandra Dupla, Anna Lesiak, Jadwiga Sołoducho, Joanna Cabaj

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引用次数: 0

摘要

病原微生物对抗生素的耐药性是世界卫生的主要问题之一。耐多药（MDR）细菌尤其令人担忧。这些微生物引起的感染会影响急性或慢性疾病的出现。在这方面，现代技术，如纳米材料（NMs），尤其是前景看好的纳米颗粒（NPs），可以具有抗菌特性或改善已知抗生素的有效性和给药方式。它们的多样性和特性，再加上表面功能化，使其能够与微生物生物大分子发生多价相互作用。本文概述了目前有关用 NPs 替代抗生素的最新研究，包括相关的前景和风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Antimicrobial activity of metal-based nanoparticles: a mini-review

The resistance of pathogenic microorganisms to antibiotics is one of the main problems of world health. Of particular concern are multidrug-resistant (MDR) bacteria. Infections caused by these microorganisms affect the appearance of acute or chronic diseases. In this regard, modern technologies, such as nanomaterials (NMs), especially promising nanoparticles (NPs), can possess antimicrobial properties or improve the effectiveness and delivery of known antibiotics. Their diversity and characteristics, combined with surface functionalization, enable multivalent interactions with microbial biomolecules. This article presents an overview of the most current research on replacing antibiotics with NPs, including the prospects and risks involved.

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来源期刊

Biometals 生物-生化与分子生物学

CiteScore

5.90

自引率

8.60%

发文量

111

审稿时长

3 months

期刊介绍： BioMetals is the only established journal to feature the important role of metal ions in chemistry, biology, biochemistry, environmental science, and medicine. BioMetals is an international, multidisciplinary journal singularly devoted to the rapid publication of the fundamental advances of both basic and applied research in this field. BioMetals offers a forum for innovative research and clinical results on the structure and function of: - metal ions - metal chelates, - siderophores, - metal-containing proteins - biominerals in all biosystems. - BioMetals rapidly publishes original articles and reviews. BioMetals is a journal for metals researchers who practice in medicine, biochemistry, pharmacology, toxicology, microbiology, cell biology, chemistry, and plant physiology who are based academic, industrial and government laboratories.