妊娠期落基山斑疹热的非典型表现。

IF 0.8 Q4 PEDIATRICS
AJP Reports Pub Date : 2024-01-23 eCollection Date: 2024-01-01 DOI:10.1055/s-0043-1778118
Jenny Wu, Sarah K Dotters-Katz, Megan Varvoutis
{"title":"妊娠期落基山斑疹热的非典型表现。","authors":"Jenny Wu, Sarah K Dotters-Katz, Megan Varvoutis","doi":"10.1055/s-0043-1778118","DOIUrl":null,"url":null,"abstract":"<p><p>Rocky Mountain spotted fever (RMSF) is a common tick-borne disease and can have variable presentation with potentially fatal outcomes when untreated. We describe an atypical presentation of RMSF in the third trimester. A 37-year-old multiparous woman at 31 <sup>0/7</sup> weeks' gestation presented normotensive with headaches and fever but no rash or significant tick exposure. She was initially treated for atypical hemolysis, elevated liver enzymes, and low platelet count syndrome but further decompensated, requiring intensive care unit transfer, intubation, and emergent delivery. Doxycycline administration was associated with marked improvement with no significant sequalae to mother or infant. Later convalescent serologies were positive for RMSF. RMSF is a clinically challenging diagnosis in pregnancy. Given significant morbidity and mortality associated with delayed treatment, high suspicion in endemic areas is needed, and prompt antibiotic use with doxycycline should be administered.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 1","pages":"e40-e42"},"PeriodicalIF":0.8000,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805569/pdf/","citationCount":"0","resultStr":"{\"title\":\"Atypical Presentation of Rocky Mountain Spotted Fever in Pregnancy.\",\"authors\":\"Jenny Wu, Sarah K Dotters-Katz, Megan Varvoutis\",\"doi\":\"10.1055/s-0043-1778118\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rocky Mountain spotted fever (RMSF) is a common tick-borne disease and can have variable presentation with potentially fatal outcomes when untreated. We describe an atypical presentation of RMSF in the third trimester. A 37-year-old multiparous woman at 31 <sup>0/7</sup> weeks' gestation presented normotensive with headaches and fever but no rash or significant tick exposure. She was initially treated for atypical hemolysis, elevated liver enzymes, and low platelet count syndrome but further decompensated, requiring intensive care unit transfer, intubation, and emergent delivery. Doxycycline administration was associated with marked improvement with no significant sequalae to mother or infant. Later convalescent serologies were positive for RMSF. RMSF is a clinically challenging diagnosis in pregnancy. Given significant morbidity and mortality associated with delayed treatment, high suspicion in endemic areas is needed, and prompt antibiotic use with doxycycline should be administered.</p>\",\"PeriodicalId\":7645,\"journal\":{\"name\":\"AJP Reports\",\"volume\":\"14 1\",\"pages\":\"e40-e42\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-01-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805569/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"AJP Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0043-1778118\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"AJP Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0043-1778118","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

摘要

落基山斑疹热(RMSF)是一种常见的蜱媒疾病,表现各异,如不及时治疗可能会导致致命后果。我们描述了洛基山斑疹热在妊娠三个月中的非典型表现。一名 37 岁的多产妇在妊娠 31 0/7 周时出现血压正常、头痛和发热,但没有皮疹或明显的蜱虫接触。她最初因非典型溶血、肝酶升高和血小板计数低综合征接受治疗,但病情进一步恶化,需要转入重症监护室、插管和紧急分娩。服用强力霉素后,病情明显好转,母婴均无明显后遗症。后来的康复血清检查显示 RMSF 呈阳性。RMSF 是妊娠期的一种临床诊断难题。鉴于延误治疗会导致严重的发病率和死亡率,因此在疾病流行地区需要高度怀疑,并应及时使用强力霉素抗生素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Atypical Presentation of Rocky Mountain Spotted Fever in Pregnancy.

Rocky Mountain spotted fever (RMSF) is a common tick-borne disease and can have variable presentation with potentially fatal outcomes when untreated. We describe an atypical presentation of RMSF in the third trimester. A 37-year-old multiparous woman at 31 0/7 weeks' gestation presented normotensive with headaches and fever but no rash or significant tick exposure. She was initially treated for atypical hemolysis, elevated liver enzymes, and low platelet count syndrome but further decompensated, requiring intensive care unit transfer, intubation, and emergent delivery. Doxycycline administration was associated with marked improvement with no significant sequalae to mother or infant. Later convalescent serologies were positive for RMSF. RMSF is a clinically challenging diagnosis in pregnancy. Given significant morbidity and mortality associated with delayed treatment, high suspicion in endemic areas is needed, and prompt antibiotic use with doxycycline should be administered.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
AJP Reports
AJP Reports PEDIATRICS-
CiteScore
2.20
自引率
0.00%
发文量
30
审稿时长
12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信