重新审视 Free-Cog:认知和执行功能对诊断的贡献。

IF 2.3 Q3 CLINICAL NEUROLOGY
Neurodegenerative disease management Pub Date : 2023-12-01 Epub Date: 2024-01-24 DOI:10.2217/nmt-2023-0013
Andrew J Larner, Alistair Burns
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引用次数: 0

摘要

目的:研究最近描述的一种混合筛查工具 Free-Cog,将其作为认知(Free-Cog-Cog)和执行功能(Free-Cog-Exec)的单独测试,以了解与标准 Free-Cog 相比,这种方法是否能提高认知障碍的筛查准确性。材料与方法使用布尔逻辑 "AND "和 "OR "运算符(串行和并行组合)将Free-Cog-Cog和Free-Cog-Exec结合起来,并用于构建逐步决策树。结果串行组合提高了特异性和阳性预测值,而并行组合提高了灵敏度,这些都是这些运算符的典型结果。逐步式应用确定了认知功能障碍的高概率组和低概率组,但未能充分区分不确定诊断的中间组。结论:研究结果表明,与标准工具相比,Free-Cog 的改良版带来的益处有限。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Free-Cog revisited: the diagnostic contribution of cognitive and executive function.

Aim: To examine Free-Cog, a recently described, hybrid screening instrument, as separate tests of cognitive (Free-Cog-Cog) and executive function (Free-Cog-Exec) to see if this improved screening accuracy for cognitive impairment compared with standard Free-Cog. Materials & methods: Free-Cog-Cog and Free-Cog-Exec were combined using Boolean logical 'AND' and 'OR' operators (serial and parallel combination), and also used to construct a stepwise decision tree. Results: Serial combination improved specificity and positive predictive value whereas parallel combination improved sensitivity, typical findings with these operators. Stepwise application identified groups with high and low probability of cognitive impairment but failed to differentiate adequately those in the intermediate uncertain diagnosis group. Conclusion: Study findings suggest limited benefit from reformulations of Free-Cog compared with the standard instrument.

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来源期刊
CiteScore
4.30
自引率
0.00%
发文量
35
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