{"title":"抑制剂阳性血友病患者靶向性血友病的同种疗法治疗:病例报告","authors":"O. Kumat, Tapas Kundu, Gulfisha Mirza, Rita Kundu","doi":"10.29121/granthaalayah.v11.i12.2023.5422","DOIUrl":null,"url":null,"abstract":"Haemarthroses is common presentation in haemophilia patient. Due to recurrent use of clotting factor concentrates for treatment and prophylaxis, of which about 20 % of patients produce antibodies to factor VIII and factor IX. This results in development of inhibitors in such patients which complicates the case even more. Homoeopathy the alternative form of treatment can be used in such case. This case report presents the management of haemarthroses in a haemophilia inhibitor. Well selected homoeopathic similimum helped in reversing the haemophilic arthropathy in left knee joint of the patient and even controlled the recurrence of the haemarthroses in target joint. The result was assessed using Hemophilia joint health assessment scale (HJHS). The result of before and after treatment was extremely significant with a p value of 0.0009 The individual curative response of the case was assessed using Modified naranjo criteria for homoeopathic case reporting, casual attribution (MONARCH).","PeriodicalId":14374,"journal":{"name":"International Journal of Research -GRANTHAALAYAH","volume":"19 5","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"HOMOEOPATHIC MANAGEMENT OF TARGETED HAEMARTHROSES IN INHIBITOR POSITIVE HAEMOPHILIAC: A CASE REPORT\",\"authors\":\"O. Kumat, Tapas Kundu, Gulfisha Mirza, Rita Kundu\",\"doi\":\"10.29121/granthaalayah.v11.i12.2023.5422\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Haemarthroses is common presentation in haemophilia patient. Due to recurrent use of clotting factor concentrates for treatment and prophylaxis, of which about 20 % of patients produce antibodies to factor VIII and factor IX. This results in development of inhibitors in such patients which complicates the case even more. Homoeopathy the alternative form of treatment can be used in such case. This case report presents the management of haemarthroses in a haemophilia inhibitor. Well selected homoeopathic similimum helped in reversing the haemophilic arthropathy in left knee joint of the patient and even controlled the recurrence of the haemarthroses in target joint. The result was assessed using Hemophilia joint health assessment scale (HJHS). The result of before and after treatment was extremely significant with a p value of 0.0009 The individual curative response of the case was assessed using Modified naranjo criteria for homoeopathic case reporting, casual attribution (MONARCH).\",\"PeriodicalId\":14374,\"journal\":{\"name\":\"International Journal of Research -GRANTHAALAYAH\",\"volume\":\"19 5\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Research -GRANTHAALAYAH\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29121/granthaalayah.v11.i12.2023.5422\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Research -GRANTHAALAYAH","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29121/granthaalayah.v11.i12.2023.5422","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
血友病是血友病患者的常见病。由于反复使用凝血因子浓缩液进行治疗和预防,其中约 20% 的患者会产生因子 VIII 和因子 IX 抗体。这导致这些患者体内产生抑制剂,使病情更加复杂。在这种情况下,可以采用同种异体疗法。本病例报告介绍了一名血友病抑制剂患者的血肿治疗方法。精心挑选的同种疗法同源物帮助患者逆转了左膝关节的血友病关节病,甚至控制了目标关节血肿的复发。治疗结果采用血友病关节健康评估量表(HJHS)进行评估。治疗前后的结果非常显著,P 值为 0.0009。病例的个体治疗反应采用同种疗法病例报告的修改纳兰霍标准(MONARCH)进行评估。
HOMOEOPATHIC MANAGEMENT OF TARGETED HAEMARTHROSES IN INHIBITOR POSITIVE HAEMOPHILIAC: A CASE REPORT
Haemarthroses is common presentation in haemophilia patient. Due to recurrent use of clotting factor concentrates for treatment and prophylaxis, of which about 20 % of patients produce antibodies to factor VIII and factor IX. This results in development of inhibitors in such patients which complicates the case even more. Homoeopathy the alternative form of treatment can be used in such case. This case report presents the management of haemarthroses in a haemophilia inhibitor. Well selected homoeopathic similimum helped in reversing the haemophilic arthropathy in left knee joint of the patient and even controlled the recurrence of the haemarthroses in target joint. The result was assessed using Hemophilia joint health assessment scale (HJHS). The result of before and after treatment was extremely significant with a p value of 0.0009 The individual curative response of the case was assessed using Modified naranjo criteria for homoeopathic case reporting, casual attribution (MONARCH).