{"title":"接触含苯及其同系物的有机溶剂工人淋巴细胞溶酶体的组织化学评价。","authors":"P Moszczyński, J Lisiewicz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The count of lymphocytes having lysosomes containing acid phosphatase (AP), beta-glucuronidase (GR) and N-acetyl-beta-D-glucosaminidase (NAG) has been estimated in the peripheral blood of 108 workers occupationally exposed to organic solvents containing benzene and its homologues. It has been stated that the prolonged exposure is associated with a reduction in the number of cells having intact acid phosphatase-positive lysosomes. The negative correlation occurring in this connection indicates the practical value of histochemical evaluation of numbers of the above cells for screening the biological effect of occupational exposure to solvents studied.</p>","PeriodicalId":76129,"journal":{"name":"Medecine interne","volume":"27 2","pages":"137-41"},"PeriodicalIF":0.0000,"publicationDate":"1989-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Histochemical evaluation of lysosomes in lymphocytes of workers having contact with organic solvents containing benzene and its homologues.\",\"authors\":\"P Moszczyński, J Lisiewicz\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The count of lymphocytes having lysosomes containing acid phosphatase (AP), beta-glucuronidase (GR) and N-acetyl-beta-D-glucosaminidase (NAG) has been estimated in the peripheral blood of 108 workers occupationally exposed to organic solvents containing benzene and its homologues. It has been stated that the prolonged exposure is associated with a reduction in the number of cells having intact acid phosphatase-positive lysosomes. The negative correlation occurring in this connection indicates the practical value of histochemical evaluation of numbers of the above cells for screening the biological effect of occupational exposure to solvents studied.</p>\",\"PeriodicalId\":76129,\"journal\":{\"name\":\"Medecine interne\",\"volume\":\"27 2\",\"pages\":\"137-41\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medecine interne\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medecine interne","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
对职业性接触含苯及其同系物的有机溶剂的108名工人外周血中含有酸性磷酸酶(AP)、β -葡糖苷酶(GR)和n -乙酰- β - d -葡糖苷酶(NAG)溶酶体的淋巴细胞计数进行了估计。已经指出，长时间暴露与具有完整的酸性磷酸酶阳性溶酶体的细胞数量减少有关。在这方面出现的负相关表明，对上述细胞数量进行组织化学评估，以筛选职业性暴露于所研究溶剂的生物效应，具有实用价值。
Histochemical evaluation of lysosomes in lymphocytes of workers having contact with organic solvents containing benzene and its homologues.
The count of lymphocytes having lysosomes containing acid phosphatase (AP), beta-glucuronidase (GR) and N-acetyl-beta-D-glucosaminidase (NAG) has been estimated in the peripheral blood of 108 workers occupationally exposed to organic solvents containing benzene and its homologues. It has been stated that the prolonged exposure is associated with a reduction in the number of cells having intact acid phosphatase-positive lysosomes. The negative correlation occurring in this connection indicates the practical value of histochemical evaluation of numbers of the above cells for screening the biological effect of occupational exposure to solvents studied.
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