Alex C. Soupir, Mary K. Townsend, Cassandra A. Hathaway, Jonathan Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Oscar E. Ospina, Lauren C. Peres, Jose R. Conejo-Garcia, Kathryn L. Terry, Shelley S. Tworoger, Brooke L. Fridley
{"title":"细胞毒性淋巴细胞和肿瘤浸润淋巴细胞的空间集群对高级别浆液性卵巢癌女性患者总生存期的影响","authors":"Alex C. Soupir, Mary K. Townsend, Cassandra A. Hathaway, Jonathan Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Oscar E. Ospina, Lauren C. Peres, Jose R. Conejo-Garcia, Kathryn L. Terry, Shelley S. Tworoger, Brooke L. Fridley","doi":"10.1101/2024.01.16.24301371","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Studies have shown that tumor infiltrating lymphocyte (TILs) abundance is associated with overall survival in patients with high-grade serous ovarian cancer (HGSOC); however, the role of the spatial contexture and organization of TILs is less clear.","PeriodicalId":501409,"journal":{"name":"medRxiv - Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of spatial clustering of cytotoxic and tumor infiltrating lymphocytes on overall survival in women with high grade serous ovarian cancer\",\"authors\":\"Alex C. Soupir, Mary K. Townsend, Cassandra A. Hathaway, Jonathan Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Oscar E. Ospina, Lauren C. Peres, Jose R. Conejo-Garcia, Kathryn L. Terry, Shelley S. Tworoger, Brooke L. Fridley\",\"doi\":\"10.1101/2024.01.16.24301371\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Background</strong> Studies have shown that tumor infiltrating lymphocyte (TILs) abundance is associated with overall survival in patients with high-grade serous ovarian cancer (HGSOC); however, the role of the spatial contexture and organization of TILs is less clear.\",\"PeriodicalId\":501409,\"journal\":{\"name\":\"medRxiv - Obstetrics and Gynecology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Obstetrics and Gynecology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.16.24301371\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Obstetrics and Gynecology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.16.24301371","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Impact of spatial clustering of cytotoxic and tumor infiltrating lymphocytes on overall survival in women with high grade serous ovarian cancer
Background Studies have shown that tumor infiltrating lymphocyte (TILs) abundance is associated with overall survival in patients with high-grade serous ovarian cancer (HGSOC); however, the role of the spatial contexture and organization of TILs is less clear.