亚甲基蓝在体内产生和还原甲基血红蛋白以及亚甲基蓝与亚硝酸钠的相互作用。

T C Marrs, J E Bright, R H Inns
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引用次数: 11

摘要

高浓度的亚甲基蓝会干扰使用IL 282 co血氧计对高血红蛋白的估计;染料不会干扰Evelyn & Malloy测定高血红蛋白的方法。在比格犬母狗中,亚甲基蓝会导致甲基血红蛋白生成和甲基血红蛋白减少,前者的作用是延缓甲基血红蛋白水平的下降,当亚甲基蓝用于逆转亚硝酸钠产生的甲基血红蛋白血症时。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Methaemoglobin production and reduction by methylene blue and the interaction of methylene blue with sodium nitrite in vivo.

Methylene blue, at high concentrations, interferes with the estimation of methaemoglobin using the IL 282 CO-oximeter: the dye does not interfere with the method of Evelyn & Malloy for determination of methaemoglobin. In beagle bitches methylene blue causes both methaemoglobinogenesis and methaemoglobin reduction, the effect of the former being to delay the decline of methaemoglobin levels, when methylene blue is used to reverse the methaemoglobinaemia produced by sodium nitrite.

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