在一名吸毒者的尸检中发现海绵状白质脑病。

Q4 Medicine

Autopsy and Case Reports Pub Date : 2024-01-08 eCollection Date: 2023-01-01 DOI:10.4322/acr.2023.465

Hemlata Jangir, Govinda Balmuchu, Jhansi Lakshmi Mylapalli, Arulselvi Subramanian, Sanjeev Lalwani

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引用次数: 0

摘要

中毒性白质脑病（TLE）是一种罕见的神经衰弱和致命疾病。以前，它与接触白细胞毒性罪犯（如化疗、颅内放射、某些药物和环境因素）有关。目前，它是一种较常见的白质综合征，由药物滥用增加引起，主要是吸入海洛因和其他阿片类药物。在此，我们报告了一例在对一名吸毒者进行尸检时发现的致命性 TLE。一名 24 岁的男性被发现死于路边。一天前，他还处于神志不清的状态。在本病例中，尸检结果和大脑皮层受累的组织病理学特征特别引导我们推测海洛因是主要的罪魁祸首。

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Spongiform leukoencephalopathy unveiled in an autopsy of a drug abuser.

Toxic leukoencephalopathy (TLE) is a rare neurological debilitating and fatal condition. It has been previously associated with exposure to leukotoxic offenders such as chemotherapy, cranial radiation, certain drugs, and environmental factors. Currently, it is a commoner white matter syndrome resulting from increased substance abuse, classically by inhaled heroin and other opioids. Herein, we report a case of fatal TLE unveiled in an autopsy of a drug abuser. A 24-year-old male was found dead on the roadside. A day before, he was located in a state of delirium. In this case, the autopsy findings and histopathology characteristics of cerebral cortex involvement particularly directed to speculate the heroine as the principal offender.

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来源期刊

Autopsy and Case Reports Medicine-Internal Medicine

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

9 weeks