1,25-二羟基胆钙化醇对正畸牙齿移动速度的作用--系统性综述

IF 0.1 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Sandra Sagar, P. Ramani, M. Yuwanati, Sagar Moses, Karthikeyan Ramalingam
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引用次数: 0

摘要

背景:众所周知,1,25-二羟基胆钙化醇是维生素 D3 的活性形式,在矿化过程中发挥着重要作用。目的:综述 1,25-二羟基胆钙化醇(维生素 D3)对正畸牙齿移动速度的作用。方法:本研究采用了系统综述的方法来分析当前文献,以界定和总结 I,25-二羟基胆钙化醇对正畸牙齿移动速度的作用。本研究使用 PubMed Central、Cochrane 系统综述数据库、Google Scholar、EMBASE 等电子数据库进行了全面搜索,并直接进行了网络搜索。结果:通过电子数据库检索,共发现 28 篇文章。根据选择标准,选出了 3 篇符合研究问题的文章。当补充 40-50 pg/dl 剂量的 1,25 二羟基胆钙化醇时,正畸牙齿移动速度提高了约 60%。根据根尖周X光片和 CBCT 的显示,服用 1,25-二羟基胆钙化醇不会对牙根或周围组织造成有害影响。结论:根据收集到的数据,局部服用活性维生素 D3(1,25-二羟基胆钙化醇)可作为一种有效的补充剂,加速正畸牙齿移动(OTM)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of 1,25 Dihydroxycholecalciferol on the Rate of Orthodontic Tooth Movement- A Systematic Review
BACKGROUND: 1,25 dihydroxycholecalciferol, the active form of vitamin D3 is known to play an important role in mineralization. Vitamin D3 is also known to have immune-supporting properties by regulating various cytokines and cell signalling pathways. AIM: To review the role of 1,25-dihydroxycholecalciferol (Vitamin D3) on the rate of Orthodontic tooth movement. METHODS: This study applied a systematic review to analyse the current literature to define and summarise the role of I,25-dihydroxycholecalciferol on the rate of Orthodontic tooth movement. A comprehensive search was done using electronic databases such as PubMed Central, Cochrane Database of Systematic Reviews, Google Scholar, EMBASE and direct web search. The title scan was done to identify relevant articles which are further evaluated for inclusion by reading the abstract. RESULTS: The electronic database search identified 28 articles. 3 articles were selected based on the selection criteria to meet the research question. There was about 60% faster rate of orthodontic tooth movement when a dosage of 40-50 pg/dl of 1,25 dihydroxycholecalciferol was supplemented. Administration of 1,25-dihydroxycholecalciferol showed no deleterious effects to the tooth roots or the surrounding tissues as evidenced from the periapical radiographs and CBCT.  CONCLUSION: Based on the collected data, the local administration of an active form of Vitamin D3, 1,25-dihydroxycholecalciferol can act as an effective supplement to accelerate Orthodontic Tooth  Movement (OTM).
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来源期刊
International Journal of Orthodontic Rehabilitation
International Journal of Orthodontic Rehabilitation DENTISTRY, ORAL SURGERY & MEDICINE-
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