在接受三维腹腔镜手术的冠心病患者中联合使用右美托咪定和瑞芬太尼并进行脑电图双谱指数监测的临床研究。

IF 1.1 Q4 ONCOLOGY
International journal of clinical and experimental pathology Pub Date : 2023-12-15 eCollection Date: 2023-01-01
Shiqi Diao, Dongxin Wang, Ying Chang, Chunyan Ni, Dongmei Fu, Jixin Liu, Song Gao, Xiunan Jia, Tongrao Wang, Xi Nan, Hongling Cao, Zongming Liu, Xitong Zhang
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引用次数: 0

摘要

研究目的本研究旨在探讨对接受三维(3D)腹腔镜手术的冠心病患者联合应用右美托咪定(Dex)和瑞芬太尼(Rem),并同时监测脑电图(EEG)双谱指数的安全性和临床效果:本研究为回顾性研究,涉及 2020 年 6 月至 2021 年 9 月期间在我院接受三维腹腔镜手术的 60 名冠心病患者。这些患者以双盲方式被随机分配到两组:对照组(I 组)和治疗组(II 组),对照组由 30 名患者组成,治疗组接受 Dex 和 Rem 的联合治疗,治疗组也由 30 名患者组成。研究的主要目的是比较和评估这两组患者的治疗效果:结果:术后出现冠心病的 II 组患者的血压、心率和心电图值(PC)显著下降:对于接受三维腹腔镜手术的冠心病患者来说,术中使用 Dex 与 Rem 麻醉相结合具有多种优势。它有助于稳定血流动力学,降低心肌缺血的风险,并显著减轻术后疼痛,所有这些都不会增加术后不良反应的可能性。此外,这种方法还能有效抑制术中和术后应激反应,促进术后恢复(ERAS)。总之,这种方法对临床的影响是积极、安全和可靠的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical study of the combined use of dexmedetomidine and remifentanil in patients with coronary heart disease undergoing 3D laparoscopic surgery with EEG bispectral index monitoring.

Objective: This study sought to investigate the safety and clinical outcomes associated with the combined administration of dexmedetomidine (Dex) and remifentanil (Rem) in patients with coronary heart disease undergoing three-dimensional (3D) laparoscopic surgery, with concurrent monitoring of the electroencephalography (EEG) bispectral index.

Methods: This study is of a retrospective nature and involved a total of 60 patients with coronary heart disease who underwent 3D laparoscopic surgery at our hospital between June 2020 and September 2021. In a double-blind manner, these patients were randomly assigned to two groups: the control group (Group I), which consisted of 30 patients, and the treatment group (Group II) receiving a combination of Dex and Rem, also comprising 30 patients. The study's primary objective was to compare and assess the treatment outcomes in these two patient groups.

Results: Patients in Group II who developed postoperative coronary heart disease experienced a significant reduction in blood pressure, heart rate, and electrocardiogram values (P<0.05). Additionally, Group II exhibited lower bispectral index (BIS) and visual analog scale (VAS) values (P<0.05).

Conclusion: In patients with coronary heart disease undergoing 3D laparoscopic surgery, the intraoperative use of Dex combined with Rem anesthesia offers several advantages. It helps stabilize hemodynamics, reducing the risk of myocardial ischemia, and significantly alleviates postoperative pain, all without increasing the likelihood of adverse postoperative reactions. Furthermore, this approach effectively dampens the intraoperative and postoperative stress response, facilitating enhanced recovery after surgery (ERAS). Overall, the clinical impact is positive, safe, and reliable.

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来源期刊
自引率
0.00%
发文量
42
审稿时长
1 months
期刊介绍: The International Journal of Clinical and Experimental Pathology (IJCEP, ISSN 1936-2625) is a peer reviewed, open access online journal. It was founded in 2008 by an international group of academic pathologists and scientists who are devoted to the scientific exploration of human disease and the rapid dissemination of original data. Unlike most other open access online journals, IJCEP will keep all the traditional features of paper print that we are all familiar with, such as continuous volume and issue numbers, as well as continuous page numbers to keep our warm feelings towards an academic journal. Unlike most other open access online journals, IJCEP will keep all the traditional features of paper print that we are all familiar with, such as continuous volume and issue numbers, as well as continuous page numbers to keep our warm feelings towards an academic journal.
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