动态对比增强磁共振成像与乳腺 X 射线摄影相结合对筛查早期乳腺癌的价值

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

African Health Sciences Pub Date : 2023-07-13 DOI:10.4314/ahs.v23i2.33

Weiwei Su, Xiaoming Hou, Bo Yu

{"title":"动态对比增强磁共振成像与乳腺 X 射线摄影相结合对筛查早期乳腺癌的价值","authors":"Weiwei Su, Xiaoming Hou, Bo Yu","doi":"10.4314/ahs.v23i2.33","DOIUrl":null,"url":null,"abstract":"Objective: To study the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in combination with mammography for screening early-stage breast cancer. Methods: Ninety-three female patients visiting Zhejiang Zhuji Hospital of Traditional Chinese Medicine from January 2020 to March 2022 were enrolled to receive DCE-MRI and mammography. The diagnostic efficiencies of different methods were assessed with pathological diagnosis as the golden standard. The factors affecting diagnostic sensitivity were investigated based on clinicopathological characteristics. Results: Forty-one patients were diagnosed as malignant pathological changes by DCE-MRI, and the signs were unclear boundary with surrounding tissues and irregular or unsmooth edges. The maximum linear slope and ratio of the maximum linear SlopeR of malignant pathological changes were significantly larger than those of benign pathological changes (P<0.05). Forty-five patients were diagnosed as malignant pathological changes by mammography combined with DCE-MRI. Compared to single diagnosis method, the combined diagnosis had significantly increased sensitivity, specificity, accuracy, positive predictive value and negative predictive value, and decreased rates of missed diagnosis and misdiagnosis (P<0.05). Lesion diameter was an independent risk factor affecting the diagnostic sensitivity (P<0.05). Conclusion: Mammography and DCE-MRI play key roles in the early diagnosis of breast cancer, and their combination can increase the diagnostic efficiency. Keywords: Breast cancer; diagnosis; magnetic resonance imaging; mammography.","PeriodicalId":7853,"journal":{"name":"African Health Sciences","volume":"190 1","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Value of dynamic contrast-enhanced magnetic resonance imaging in combination with mammography for screening early-stage breast cancer\",\"authors\":\"Weiwei Su, Xiaoming Hou, Bo Yu\",\"doi\":\"10.4314/ahs.v23i2.33\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To study the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in combination with mammography for screening early-stage breast cancer. Methods: Ninety-three female patients visiting Zhejiang Zhuji Hospital of Traditional Chinese Medicine from January 2020 to March 2022 were enrolled to receive DCE-MRI and mammography. The diagnostic efficiencies of different methods were assessed with pathological diagnosis as the golden standard. The factors affecting diagnostic sensitivity were investigated based on clinicopathological characteristics. Results: Forty-one patients were diagnosed as malignant pathological changes by DCE-MRI, and the signs were unclear boundary with surrounding tissues and irregular or unsmooth edges. The maximum linear slope and ratio of the maximum linear SlopeR of malignant pathological changes were significantly larger than those of benign pathological changes (P<0.05). Forty-five patients were diagnosed as malignant pathological changes by mammography combined with DCE-MRI. Compared to single diagnosis method, the combined diagnosis had significantly increased sensitivity, specificity, accuracy, positive predictive value and negative predictive value, and decreased rates of missed diagnosis and misdiagnosis (P<0.05). Lesion diameter was an independent risk factor affecting the diagnostic sensitivity (P<0.05). Conclusion: Mammography and DCE-MRI play key roles in the early diagnosis of breast cancer, and their combination can increase the diagnostic efficiency. Keywords: Breast cancer; diagnosis; magnetic resonance imaging; mammography.\",\"PeriodicalId\":7853,\"journal\":{\"name\":\"African Health Sciences\",\"volume\":\"190 1\",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2023-07-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"African Health Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4314/ahs.v23i2.33\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Health Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4314/ahs.v23i2.33","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

摘要

目的研究动态对比增强磁共振成像（DCE-MRI）与乳腺 X 光造影术相结合对早期乳腺癌筛查的价值。方法：在浙江诸暨医院就诊的 93 名女性患者：选取 2020 年 1 月至 2022 年 3 月期间在浙江省诸暨市中医院就诊的 93 例女性患者作为研究对象，接受 DCE-MRI 和乳腺 X 线造影检查。以病理诊断为黄金标准，评估不同方法的诊断效率。根据临床病理特征研究了影响诊断灵敏度的因素。结果：41 例患者经 DCE-MRI 诊断为恶性病变，表现为与周围组织边界不清、边缘不规则或不光滑。恶性病变的最大线性斜率和最大线性斜率比明显大于良性病变（P<0.05）。45 例患者通过乳腺 X 线造影联合 DCE-MRI 诊断为恶性病变。与单一诊断方法相比，联合诊断的敏感性、特异性、准确性、阳性预测值和阴性预测值均有明显提高，漏诊率和误诊率均有所下降（P<0.05）。病变直径是影响诊断灵敏度的独立风险因素（P<0.05）。结论乳腺钼靶X线摄影和DCE-MRI在乳腺癌的早期诊断中起着关键作用，二者结合可提高诊断效率。关键词：乳腺癌；诊断；磁共振成像乳腺癌；诊断；磁共振成像；乳腺X光检查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Value of dynamic contrast-enhanced magnetic resonance imaging in combination with mammography for screening early-stage breast cancer

Objective: To study the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in combination with mammography for screening early-stage breast cancer. Methods: Ninety-three female patients visiting Zhejiang Zhuji Hospital of Traditional Chinese Medicine from January 2020 to March 2022 were enrolled to receive DCE-MRI and mammography. The diagnostic efficiencies of different methods were assessed with pathological diagnosis as the golden standard. The factors affecting diagnostic sensitivity were investigated based on clinicopathological characteristics. Results: Forty-one patients were diagnosed as malignant pathological changes by DCE-MRI, and the signs were unclear boundary with surrounding tissues and irregular or unsmooth edges. The maximum linear slope and ratio of the maximum linear SlopeR of malignant pathological changes were significantly larger than those of benign pathological changes (P<0.05). Forty-five patients were diagnosed as malignant pathological changes by mammography combined with DCE-MRI. Compared to single diagnosis method, the combined diagnosis had significantly increased sensitivity, specificity, accuracy, positive predictive value and negative predictive value, and decreased rates of missed diagnosis and misdiagnosis (P<0.05). Lesion diameter was an independent risk factor affecting the diagnostic sensitivity (P<0.05). Conclusion: Mammography and DCE-MRI play key roles in the early diagnosis of breast cancer, and their combination can increase the diagnostic efficiency. Keywords: Breast cancer; diagnosis; magnetic resonance imaging; mammography.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

African Health Sciences MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

0.00%

发文量

179

审稿时长

>12 weeks

期刊介绍： The African Health Sciences is an internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. Its objectives are to: Advocate for and promote the growth of reading culture in sub Saharan Africa; Provide a high quality journal in which health and policy and other researchers and practitioners in the region can and world wide, can publish their work; Promote relevant health system research and publication in the region including alternative means of health care financing, the burden of and solution of health problems in marginalized urban and rural communities amongst the displaced and others affected by conflict; Promote research and the systematic collection and collation and publication of data on diseases and conditions of equity and influence; Promote development of evidence-based policies and guidelines for clinical, public health and other practitioners. African Health Sciences acknowledges support provided by the African Health Journals Partnership Project that is funded by the US National Institutes of Health (through the National Library of Medicine and the Fogarty International Center) and facilitated by the Council of Science Editors.