Locally advanced squamous cell carcinoma gallbladder: A case report

Carcinoma gallbladder is a common hepatobiliary malignancy with aggressive biological behavior. Most common histopathological variant is adenocarcinoma (>90%). Squamous cell carcinoma is an uncommon variant of carcinoma gallbladder. Its clinical presentation is similar to those with adenocarcinoma. They grow very rapidly and has diffuse hepatic and local organ infiltrations. Early detection and radical surgical resection remain the cornerstone of the definitive management. We report a case of locally advanced carcinoma gallbladder of squamous cell variant. Patient presented with features of acute cholecystitis and had palpable gallbladder mass. Clinically and radiologically, she was diagnosed as a case of carcinoma gallbladder and underwent exploratory laparotomy, radical cholecystectomy with right hemicolectomy. Post operative histopathological examination confirmed squamous cell carcinoma of gallbladder.