{"title":"针对 PLpro 靶点的部分 FDA 批准药物的虚拟筛选和结合模式分析：努力确定抗击 COVID-19 的疗法","authors":"M. Ashouri","doi":"10.52768/2993-1142/1070","DOIUrl":null,"url":null,"abstract":"Papain-like protease (PLpro) is one of the most promising targets for anti-SARS-CoV drugs because it is an essential multifunctional cysteine protease for corona viral replication.","PeriodicalId":74134,"journal":{"name":"Med discoveries","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Virtual Screening and Binding Mode Analysis of Selected FDA Approved Drugs Against PLpro Target: An Effort to Identify Therapeutics to Combat COVID-19\",\"authors\":\"M. Ashouri\",\"doi\":\"10.52768/2993-1142/1070\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Papain-like protease (PLpro) is one of the most promising targets for anti-SARS-CoV drugs because it is an essential multifunctional cysteine protease for corona viral replication.\",\"PeriodicalId\":74134,\"journal\":{\"name\":\"Med discoveries\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Med discoveries\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52768/2993-1142/1070\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Med discoveries","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52768/2993-1142/1070","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Virtual Screening and Binding Mode Analysis of Selected FDA Approved Drugs Against PLpro Target: An Effort to Identify Therapeutics to Combat COVID-19
Papain-like protease (PLpro) is one of the most promising targets for anti-SARS-CoV drugs because it is an essential multifunctional cysteine protease for corona viral replication.
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