血红蛋白红细胞分布宽度比作为局部晚期肺腺癌患者的预后指标

Hasret Gizem Kurt, Ayperi Öztürk, Figen ÖZTÜRK ERGÜR
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引用次数: 0

摘要

目的:血红蛋白/红细胞分布宽度比(HRR)已被定义为各种恶性肿瘤的有效预后因素。本研究旨在探讨 HRR 在局部晚期肺腺癌中的预后作用。 方法:筛选出 626 例确诊为局部晚期肺腺癌的患者。通过ROC分析确定HRR对总生存期(OS)和无进展生存期(PFS)的最佳临界点。确定了 HRR 临界值后,患者被分为 HRR 较低和较高两组。比较两组患者的临床、人口统计学和实验室数值。为了确定预后的独立预测因素,采用了多变量考克斯回归分析。 结果共纳入 119 名患者。确定 OS 的最佳 HRR 临界点为 0.963%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hemoglobin red cell distribution width ratio as a prognostic marker in patients with locally advanced lung adenocarcinoma
Aims: Hemoglobin/red cell distribution width ratio (HRR) has been defined as an effective prognostic factor in various malignancies. The aim of this study is to investigate the prognostic role of HRR in locally advanced lung adenocarcinoma. Methods: 626 patients diagnosed with locally advanced lung adenocarcinoma were screened. The best cut-off point of HRR for overall survival (OS) and progression free survival (PFS) was determined by ROC analysis. A HRR cut-off value was determined, patients were classified as having lower or higher HRR. Both groups’ clinical, demographic, laboratory values were compared. To identify independent predictors of prognosis, multivariate cox regression analysis was used. Results: A total of119 patients were included. The best cut-off point of HRR in determining OS was 0.963%.HRR below the cut-off value increased mortality by 2.2fold.The group with HRR
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