{"title":"血红蛋白红细胞分布宽度比作为局部晚期肺腺癌患者的预后指标","authors":"Hasret Gizem Kurt, Ayperi Öztürk, Figen ÖZTÜRK ERGÜR","doi":"10.38053/acmj.1322201","DOIUrl":null,"url":null,"abstract":"Aims: Hemoglobin/red cell distribution width ratio (HRR) has been defined as an effective prognostic factor in various malignancies. The aim of this study is to investigate the prognostic role of HRR in locally advanced lung adenocarcinoma. Methods: 626 patients diagnosed with locally advanced lung adenocarcinoma were screened. The best cut-off point of HRR for overall survival (OS) and progression free survival (PFS) was determined by ROC analysis. A HRR cut-off value was determined, patients were classified as having lower or higher HRR. Both groups’ clinical, demographic, laboratory values were compared. To identify independent predictors of prognosis, multivariate cox regression analysis was used. Results: A total of119 patients were included. The best cut-off point of HRR in determining OS was 0.963%.HRR below the cut-off value increased mortality by 2.2fold.The group with HRR","PeriodicalId":307693,"journal":{"name":"Anatolian Current Medical Journal","volume":"44 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hemoglobin red cell distribution width ratio as a prognostic marker in patients with locally advanced lung adenocarcinoma\",\"authors\":\"Hasret Gizem Kurt, Ayperi Öztürk, Figen ÖZTÜRK ERGÜR\",\"doi\":\"10.38053/acmj.1322201\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aims: Hemoglobin/red cell distribution width ratio (HRR) has been defined as an effective prognostic factor in various malignancies. The aim of this study is to investigate the prognostic role of HRR in locally advanced lung adenocarcinoma. Methods: 626 patients diagnosed with locally advanced lung adenocarcinoma were screened. The best cut-off point of HRR for overall survival (OS) and progression free survival (PFS) was determined by ROC analysis. A HRR cut-off value was determined, patients were classified as having lower or higher HRR. Both groups’ clinical, demographic, laboratory values were compared. To identify independent predictors of prognosis, multivariate cox regression analysis was used. Results: A total of119 patients were included. The best cut-off point of HRR in determining OS was 0.963%.HRR below the cut-off value increased mortality by 2.2fold.The group with HRR\",\"PeriodicalId\":307693,\"journal\":{\"name\":\"Anatolian Current Medical Journal\",\"volume\":\"44 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anatolian Current Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.38053/acmj.1322201\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anatolian Current Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.38053/acmj.1322201","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hemoglobin red cell distribution width ratio as a prognostic marker in patients with locally advanced lung adenocarcinoma
Aims: Hemoglobin/red cell distribution width ratio (HRR) has been defined as an effective prognostic factor in various malignancies. The aim of this study is to investigate the prognostic role of HRR in locally advanced lung adenocarcinoma. Methods: 626 patients diagnosed with locally advanced lung adenocarcinoma were screened. The best cut-off point of HRR for overall survival (OS) and progression free survival (PFS) was determined by ROC analysis. A HRR cut-off value was determined, patients were classified as having lower or higher HRR. Both groups’ clinical, demographic, laboratory values were compared. To identify independent predictors of prognosis, multivariate cox regression analysis was used. Results: A total of119 patients were included. The best cut-off point of HRR in determining OS was 0.963%.HRR below the cut-off value increased mortality by 2.2fold.The group with HRR