苏丹正常妊娠妇女的母体和新生儿脐带血清中 25-羟基维生素 D 的水平：一项横断面研究

IF 0.1 0 MEDICINE, GENERAL & INTERNAL

Gazzetta Medica Italiana Archivio per le Scienze Mediche Pub Date : 2023-11-01 DOI:10.23736/s0393-3660.23.05029-5

M. Ahmed, Abdelmageed Elmugabil, Ashwaq AlEed, Abdullah Al-Nafeesah, Ishag Adam

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引用次数: 0

摘要

关于撒哈拉以南非洲地区母体和脐带血清维生素 D 浓度之间关系的公开研究很少。因此，本研究旨在评估母亲和脐带 25- 羟维生素 D（25-[OH]D）水平之间的关系。这项横断面研究在苏丹喀土穆的 Saad Abuelela 妇产医院进行。共登记了 90 对母亲和新生儿（脐带）。母亲年龄和胎龄的中位数（IQR）分别为 28.5（26.0 - 30.0）岁和 38.0（37.5 - 38.2）周。脐带25-（OH）D的中位数（IQR）明显高于母体25-（OH）D的中位数（30.3 [18.2 - 38.4] vs. 20.2 [17.5], ng/mL，P = 0.011）。此外，与母体样本相比，脐带样本中维生素D缺乏率明显偏低（≤20；25/90 [27.8%] vs. 42/90 [46.7%]，P = 0.013）。脐带25-(OH)D水平与母体25-(OH)D水平呈正相关，且显著高于母体25-(OH)D水平（r = 0.401）。

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Maternal and neonatal umbilical cord serum levels of 25-hydroxy vitamin D among Sudanese women with normal pregnancy: a cross-sectional study

There are few published studies on the association between maternal and umbilical cord serum vitamin D concentrations in Sub-Saharan Africans. Therefore, the aim of this study was to assess the association between mothers and umbilical cord 25-hydroxyvitamin D (25-[OH)]D) levels. A cross-sectional study was conducted at the Saad Abuelela Maternity Hospital in Khartoum, Sudan. 90 pairs of mothers and neonates (umbilical cords) were enrolled. The median (IQR) mother’s age and gestational age were 28.5 (26.0 ‒ 30.0) years and 38.0 (37.5 ‒ 38.2) weeks, respectively. The median (IQR) umbilical cord level of 25-(OH)D was signi�cantly higher than the median maternal level of 25-(OH)D (30.3 [18.2 ‒ 38.4] vs. 20.2 [17.5], ng/mL, P = 0.011). Moreover, compared to the maternal samples, a signi�cantly low number of umbilical cord samples had a vitamin D de�ciency ( ≤ 20; 25/90 [27.8%] vs. 42/90 [46.7%], P = 0.013). The umbilical cord 25-(OH)D levels were positively correlated with and signi�cantly higher than the maternal 25-(OH)D levels (r = 0.401).

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来源期刊

Gazzetta Medica Italiana Archivio per le Scienze Mediche MEDICINE, GENERAL & INTERNAL-

CiteScore

0.20

自引率

0.00%

发文量

136

期刊介绍： The journal Gazzetta Medica Italiana publishes scientific papers on medicine and pharmacology. Manuscripts may be submitted in the form of editorials, original articles, review articles, case reports, therapeutical notes, special articles and letters to the Editor. Manuscripts are expected to comply with the instructions to authors which conform to the Uniform Requirements for Manuscripts Submitted to Biomedical Editors by the International Committee of Medical Journal Editors (www.icmje.org). Articles not conforming to international standards will not be considered for acceptance.