建立乳腺癌表型模型时肿瘤细胞的表型组成及其在转移过程中的作用

Cardiometry Pub Date : 2023-11-01 DOI:10.18137/cardiometry.2023.29.conf.3

U. A. Bokova, M. Tretyakova, A.A. Frolova, V. Alifanov, E. S. Andryukhova, N. Cherdyntseva, V. Perelmuter, E. Denisov

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引用次数: 0

摘要

研究转移机制的有效工具之一是使用原发患者肿瘤的小鼠模型（Patient-Derived Xenograft，PDX）。细胞表型随肿瘤微环境的动态变化而变化的现象是转移的关键过程之一。

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PHENOTYPIC COMPOSITION OF TUMOR CELLS AND THEIR ROLE IN THE PROCESS OF METASTASIS WHEN DEVELOPING A PDX MODEL OF BREAST CANCER

To study the mechanisms of metastasis, one of the effective tools is mouse models using primary patient tumors (Patient-Derived Xenograft, PDX). The phenomenon of changes in the cell phenotype in response to the dynamic conditions of the tumor microenvironment is one of the key processes forming the basis for metastasis.

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来源期刊

Cardiometry MEDICAL LABORATORY TECHNOLOGY-

自引率

0.00%

发文量

审稿时长

6 weeks

期刊介绍： Cardiometry is an open access biannual electronic journal founded in 2012. It refers to medicine, particularly to cardiology, as well as oncocardiology and allied science of biophysics and medical equipment engineering. We publish mainly high quality original articles, reports, case reports, reviews and lectures in the field of the theory of cardiovascular system functioning, principles of cardiometry, its diagnostic methods, cardiovascular system therapy from the aspect of cardiometry, system and particular approaches to maintaining health, engineering peculiarities in cardiometry developing. The interdisciplinary areas of the journal are: hemodynamics, biophysics, biochemistry, metrology. The target audience of our Journal covers healthcare providers including cardiologists and general practitioners, bioengineers, biophysics, medical equipment, especially cardiology diagnostics device, developers, educators, nurses, healthcare decision-makers, people with cardiovascular diseases, cardiology and engineering universities and schools, state and private clinics. Cardiometry is aimed to provide a wide forum for exchange of information and public discussion on above scientific issues for the mentioned experts.