曲马多 - 分娩镇痛药

Janaki Vellanki, Velpula Sushma Sri
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引用次数: 0

摘要

:分娩过程中的疼痛管理是良好产科护理的重要组成部分。虽然分娩时的剧烈疼痛不会危及生命,但会对生理和神经心理造成影响。分娩过程中适当的镇痛对产妇有益,对分娩过程和新生儿的状态也有积极影响。理想的产科镇痛药应具有类似阿片类药物的强效镇痛效果,同时副作用最小。曲马多可作为一种基本镇痛药,用于治疗中度至重度疼痛患者。经机构伦理委员会批准,该研究于 2022 年 4 月至 2023 年 3 月在海得拉巴甘地医学院和医院妇产科进行,为期一年。500 名 18 至 35 岁的产妇被分为两组,对照组和研究组各 250 人。使用的药物是肌肉注射盐酸曲马多,剂量为 1 安瓿 2 毫升,其中 1 毫升相当于 50 毫克。据观察,与对照组相比,肌肉注射曲马多后疼痛程度明显减轻。大多数患者的新生儿预后良好,产妇无并发症,产程缩短。研究组分别有 10%和 43.2%的患者出现三级和四级疼痛,而对照组分别有 13.2%和 54.4%的患者出现三级和四级疼痛,差异具有统计学意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tramadol – A wonder drug in women with labour pain
: Pain management during labour is an essential part of good obstetric care. Though this severe pain during labour is not life-threatening, it can have physiological and neuropsychological consequences. Adequate analgesia during labour is a benefit for the mother, has a positive influence on the course of labour and the state of the new born child. The ideal analgesic in obstetrics should have potent opiate-like analgesic efficacy with minimal side effects. Tramadol can be used as a basic analgesic for the treatment of patients with moderate to severe pain. Parenteral tramadol during labour was proven to have no negative effects on the baby or the process of labour.The study was conducted for a period of one year from April 2022 to March 2023 in the Department of obstetrics and Gynaecology, Gandhi Medical College and Hospital, Hyderabad after approval from Institutional Ethics Committee. Total of 500 parturient of age group 18 to 35 years were divided into 2 groups, control and study groups 250 participants each. The drug utilized was Intramuscular Tramadol Hydrochloride at a dosage of 1 ampule containing 2 ml, where 1 ml is equivalent to 50 mg. It is observed that there was a significant decrease in the degree of pain when compared to control group after giving Intramuscular Tramadol injection. And the majority of the patients had good neonatal outcomes and no maternal complications and reduced the duration of labour. In the study group 10% and 43.2% of patients, whereas 13.2% and 54.4% of patient in control group had Grade III and Grade IV pain, which was statistically significant.Intramuscular Tramadol Injection is safe for both mother and baby, effective and shortens the duration of labour period.
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