波兰血脂协会认可的波兰专家组关于在波兰使用匹伐他汀治疗血脂紊乱的立场文件。

IF 3 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Maciej Banach, Stanisław Surma, A. Kapłon-Cieślicka, Przemysław Mitkowski, Grzegorz Dzida, Tomasz Tomasik, A. Mastalerz-Migas
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引用次数: 0

摘要

低密度脂蛋白胆固醇(LDL-C)是确定心血管风险应测量的基本血脂参数,也决定了 LLT 的目的和目标。在心血管一级和二级预防中,低密度脂蛋白胆固醇治疗可改善心血管预后并延长生命。尽管目前已有有效的降脂药物,也有可靠的数据证明其有益作用,但低密度脂蛋白胆固醇的控制水平仍然很低。这与医生的惰性和患者对副作用的恐惧有关。血脂学的发展使药物具有良好的安全性,并实现了个性化治疗。匹伐他汀是药效排名第三的他汀类药物,其特点是由于代谢方式不同,发生肌肉并发症和 NOD 的风险较低。因此,匹伐他汀是糖尿病高风险患者或现有糖尿病患者以及心血管高风险患者的良好治疗选择。本立场文件指出了匹伐他汀在血脂紊乱治疗中的地位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Position Paper of the Polish Expert Group on the Use of Pitavastatin in the Treatment of Lipid Disorders in Poland Endorsed by the Polish Lipid Association.
LDL-C is the basic lipid parameter that should be measured to determine CV risk and determines the aim and LLT target. LLT improves cardiovascular prognosis and prolongs life in both primary and secondary cardiovascular prevention. Despite the availability of effective lipid-lowering drugs and solid data on their beneficial effects, the level of LDL-C control is highly insufficient. This is related to physician inertia and patients' fear of side effects. The development of lipidology has made drugs available with a good safety profile and enabling personalisation of therapy. Pitavastatin, the third most potent statin, is characterised by a lower risk of muscle complications and NOD due to its being metabolised differently. Thus, pitavastatin is a good therapeutic option in patients at high risk of diabetes or with existing diabetes, and in patients at cardiovascular risk. This Position Paper indicates the place of using pitavastatin in the treatment of lipid disorders.
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来源期刊
Archives of Medical Science
Archives of Medical Science 医学-医学:内科
CiteScore
4.90
自引率
7.90%
发文量
139
审稿时长
1.7 months
期刊介绍: Archives of Medical Science (AMS) publishes high quality original articles and reviews of recognized scientists that deal with all scientific medicine. AMS opens the possibilities for young, capable scientists. The journal would like to give them a chance to have a publication following matter-of-fact, professional review by outstanding, famous medical scientists. Thanks to that they will have an opportunity to present their study results and/or receive useful advice about the mistakes they have made so far. The second equally important aim is a presentation of review manuscripts of recognized scientists about the educational capacity, in order that young scientists, often at the beginning of their scientific carrier, could constantly deepen their medical knowledge and be up-to-date with current guidelines and trends in world-wide medicine. The fact that our educational articles are written by world-famous scientists determines their innovation and the highest quality.
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