{"title":"类风湿关节炎患者代谢功能障碍相关性脂肪肝发生纤维化的风险","authors":"Murat Aydın, Berrin Aksakal, S. Basat","doi":"10.4274/imj.galenos.2023.42949","DOIUrl":null,"url":null,"abstract":"), PLT count (p<0.001), and alanine aminotransferase values (p<0.05) (r=0.956). Conclusion: Our study highlights that patients with both MAFLD and RA face a heightened risk of fibrosis progression compared with those without RA. While existing literature acknowledges MAFLD’s association with liver fibrosis, there is a scarcity of research on RA’s influence in this context. Our findings emphasize RA as an additional risk factor for liver fibrosis, particularly among patients with MAFLD. Consequently, liver fibrosis is more prevalent in patients with MAFLD and RA.","PeriodicalId":42584,"journal":{"name":"Istanbul Medical Journal","volume":"43 1","pages":""},"PeriodicalIF":0.2000,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Risk of the Development of Fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease in Patients with Rheumatoid Arthritis\",\"authors\":\"Murat Aydın, Berrin Aksakal, S. Basat\",\"doi\":\"10.4274/imj.galenos.2023.42949\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"), PLT count (p<0.001), and alanine aminotransferase values (p<0.05) (r=0.956). Conclusion: Our study highlights that patients with both MAFLD and RA face a heightened risk of fibrosis progression compared with those without RA. While existing literature acknowledges MAFLD’s association with liver fibrosis, there is a scarcity of research on RA’s influence in this context. Our findings emphasize RA as an additional risk factor for liver fibrosis, particularly among patients with MAFLD. Consequently, liver fibrosis is more prevalent in patients with MAFLD and RA.\",\"PeriodicalId\":42584,\"journal\":{\"name\":\"Istanbul Medical Journal\",\"volume\":\"43 1\",\"pages\":\"\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2023-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Istanbul Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4274/imj.galenos.2023.42949\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Istanbul Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/imj.galenos.2023.42949","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
)、PLT 计数(P<0.001)和丙氨酸氨基转移酶值(P<0.05)(r=0.956)。结论我们的研究强调,与没有RA的患者相比,同时患有MAFLD和RA的患者面临更高的纤维化进展风险。虽然现有文献承认 MAFLD 与肝纤维化有关,但有关 RA 在这方面影响的研究却很少。我们的研究结果强调了 RA 是肝纤维化的额外风险因素,尤其是在 MAFLD 患者中。因此,肝纤维化在MAFLD和RA患者中更为普遍。
Risk of the Development of Fibrosis in Metabolic Dysfunction-Associated Fatty Liver Disease in Patients with Rheumatoid Arthritis
), PLT count (p<0.001), and alanine aminotransferase values (p<0.05) (r=0.956). Conclusion: Our study highlights that patients with both MAFLD and RA face a heightened risk of fibrosis progression compared with those without RA. While existing literature acknowledges MAFLD’s association with liver fibrosis, there is a scarcity of research on RA’s influence in this context. Our findings emphasize RA as an additional risk factor for liver fibrosis, particularly among patients with MAFLD. Consequently, liver fibrosis is more prevalent in patients with MAFLD and RA.