{"title":"帕梅卡山市市场上无品牌速溶草药饮料中的环丙氨酸盐含量分析","authors":"Nur Jamila, Alief Putriana Rahman, Fauzan Humaidi","doi":"10.20473/bikfar.v10i2.51955","DOIUrl":null,"url":null,"abstract":"Jamu is one of the traditional medicines because most herbal medicine uses natural ingredients or plants. One of the safety of herbal medicine is the absence of abuse such as the addition of artificial sweeteners in the form of cyclamate. Cyclamate is one of the artificial sweeteners that has a sweetness level 30 times higher than natural sweeteners. Excessive use of cyclamate will cause cancer and tumors. The purpose of this study is to determine the presence or absence of cyclamate content and levels in ready-to-drink herbal medicine without a brand sold in the Pamekasan City market. This research was conducted qualitatively with precipitation methods and quantitative with gravimetric methods. From qualitative research, the results of sample A found a white precipitate which indicates a positive sample containing cyclamate. While samples B and C found no deposits indicating that the sample was negative cyclamate. Furthermore, a positive sample is carried out quantitative testing. In determining cyclamate levels, sodium cyclamate levels in sample A were obtained at 4.8047 g/kg. so that the serving rate or per 1 bottle of herbal medicine contains 115.312 g/0.6 kg and this exceeds the threshold determined by BPOM Regulations which is 1.25 g/kg. The conclusion of this study is that 1 out of 3 positive samples contains cyclamate with levels that exceed the threshold determined by BPOM RI No. 32 of 2019.","PeriodicalId":8835,"journal":{"name":"Berkala Ilmiah Kimia Farmasi","volume":"78 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of Cyclamate Content in Unbranded Instant Herbal Medicinal Drink on Market in the City of Pamekasan\",\"authors\":\"Nur Jamila, Alief Putriana Rahman, Fauzan Humaidi\",\"doi\":\"10.20473/bikfar.v10i2.51955\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Jamu is one of the traditional medicines because most herbal medicine uses natural ingredients or plants. One of the safety of herbal medicine is the absence of abuse such as the addition of artificial sweeteners in the form of cyclamate. Cyclamate is one of the artificial sweeteners that has a sweetness level 30 times higher than natural sweeteners. Excessive use of cyclamate will cause cancer and tumors. The purpose of this study is to determine the presence or absence of cyclamate content and levels in ready-to-drink herbal medicine without a brand sold in the Pamekasan City market. This research was conducted qualitatively with precipitation methods and quantitative with gravimetric methods. From qualitative research, the results of sample A found a white precipitate which indicates a positive sample containing cyclamate. While samples B and C found no deposits indicating that the sample was negative cyclamate. Furthermore, a positive sample is carried out quantitative testing. In determining cyclamate levels, sodium cyclamate levels in sample A were obtained at 4.8047 g/kg. so that the serving rate or per 1 bottle of herbal medicine contains 115.312 g/0.6 kg and this exceeds the threshold determined by BPOM Regulations which is 1.25 g/kg. The conclusion of this study is that 1 out of 3 positive samples contains cyclamate with levels that exceed the threshold determined by BPOM RI No. 32 of 2019.\",\"PeriodicalId\":8835,\"journal\":{\"name\":\"Berkala Ilmiah Kimia Farmasi\",\"volume\":\"78 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Berkala Ilmiah Kimia Farmasi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.20473/bikfar.v10i2.51955\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Berkala Ilmiah Kimia Farmasi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20473/bikfar.v10i2.51955","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
Jamu 是传统药物之一,因为大多数草药都使用天然成分或植物。草药的安全性之一是不会被滥用,如添加甜蜜素形式的人工甜味剂。甜蜜素是一种人工甜味剂,其甜度是天然甜味剂的 30 倍。过量使用甜蜜素会导致癌症和肿瘤。本研究的目的是确定在 Pamekasan 市市场上销售的无品牌即饮草药中是否含有环己基氨基甲酸酯及其含量。本研究采用沉淀法进行定性研究,采用重量法进行定量研究。定性研究结果显示,样品 A 发现了白色沉淀,表明样品中含有环己基氨基甲酸酯。而样品 B 和 C 没有发现沉淀物,表明样品中的甜蜜素为阴性。此外,还对阳性样品进行了定量检测。在确定甜蜜素含量时,A 样品中的甜蜜素含量为 4.8047 克/千克,因此每瓶中药的食用量或含量为 115.312 克/0.6 千克,超过了《口腔健康条例》规定的阈值(1.25 克/千克)。这项研究的结论是,在 3 个阳性样品中,有 1 个样品中的甜蜜素含量超过了 BPOM RI 2019 年第 32 号规定所确定的阈值。
Analysis of Cyclamate Content in Unbranded Instant Herbal Medicinal Drink on Market in the City of Pamekasan
Jamu is one of the traditional medicines because most herbal medicine uses natural ingredients or plants. One of the safety of herbal medicine is the absence of abuse such as the addition of artificial sweeteners in the form of cyclamate. Cyclamate is one of the artificial sweeteners that has a sweetness level 30 times higher than natural sweeteners. Excessive use of cyclamate will cause cancer and tumors. The purpose of this study is to determine the presence or absence of cyclamate content and levels in ready-to-drink herbal medicine without a brand sold in the Pamekasan City market. This research was conducted qualitatively with precipitation methods and quantitative with gravimetric methods. From qualitative research, the results of sample A found a white precipitate which indicates a positive sample containing cyclamate. While samples B and C found no deposits indicating that the sample was negative cyclamate. Furthermore, a positive sample is carried out quantitative testing. In determining cyclamate levels, sodium cyclamate levels in sample A were obtained at 4.8047 g/kg. so that the serving rate or per 1 bottle of herbal medicine contains 115.312 g/0.6 kg and this exceeds the threshold determined by BPOM Regulations which is 1.25 g/kg. The conclusion of this study is that 1 out of 3 positive samples contains cyclamate with levels that exceed the threshold determined by BPOM RI No. 32 of 2019.