Andréa Mazza Beliero1,2, Ana Paula Pires Lázaro3,4, Marza de Sousa Zaranza1,5, Giovanna Mazza Cruz Lima4, Álvaro Rolim Guimarães5, Nilcyeli Linhares Aragão5, Gdayllon Cavalcante Meneses5, Marcelo Alcantara Holanda5,6, Polianna Lemos Moura Moreira Albuquerque4,7, Geraldo Bezerra da Silva Júnior3,4, Paula Frassinetti Castelo Branco Camurça Fernandes2
{"title":"ELMO CPAP:用于治疗 COVID-19 相关急性呼吸窘迫综合征的创新型通气支持技术","authors":"Andréa Mazza Beliero1,2, Ana Paula Pires Lázaro3,4, Marza de Sousa Zaranza1,5, Giovanna Mazza Cruz Lima4, Álvaro Rolim Guimarães5, Nilcyeli Linhares Aragão5, Gdayllon Cavalcante Meneses5, Marcelo Alcantara Holanda5,6, Polianna Lemos Moura Moreira Albuquerque4,7, Geraldo Bezerra da Silva Júnior3,4, Paula Frassinetti Castelo Branco Camurça Fernandes2","doi":"10.36416/1806-3756/e20230227","DOIUrl":null,"url":null,"abstract":"Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is a retrospective study of 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected on ICU admission, as well as before, during, and after ELMO use. Patients were divided into two groups (success and failure) according to the outcome. Results: ELMO use improved oxygenation parameters such as Pao2, Fio2, and the Pao2/Fio2 ratio, and this contributed to a gradual reduction in Fio2, without an increase in CO2, as determined by arterial blood gas analysis. Patients in the success group had significantly longer survival (p < 0.001), as determined by the Kaplan-Meier analysis, less need for intubation (p < 0.001), fewer days of hospitalization, and a lower incidence of acute kidney injury in comparison with those in the failure group. Conclusions: The significant improvement in oxygenation parameters, the longer survival, as reflected by the reduced need for intubation and by the mortality rate, and the absence of acute kidney injury suggest that the ELMO CPAP system is a promising tool for treating ARDS and similar clinical conditions.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"46 2","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ELMO CPAP: an innovative type of ventilatory support for COVID-19-related acute respiratory distress syndrome\",\"authors\":\"Andréa Mazza Beliero1,2, Ana Paula Pires Lázaro3,4, Marza de Sousa Zaranza1,5, Giovanna Mazza Cruz Lima4, Álvaro Rolim Guimarães5, Nilcyeli Linhares Aragão5, Gdayllon Cavalcante Meneses5, Marcelo Alcantara Holanda5,6, Polianna Lemos Moura Moreira Albuquerque4,7, Geraldo Bezerra da Silva Júnior3,4, Paula Frassinetti Castelo Branco Camurça Fernandes2\",\"doi\":\"10.36416/1806-3756/e20230227\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is a retrospective study of 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected on ICU admission, as well as before, during, and after ELMO use. Patients were divided into two groups (success and failure) according to the outcome. Results: ELMO use improved oxygenation parameters such as Pao2, Fio2, and the Pao2/Fio2 ratio, and this contributed to a gradual reduction in Fio2, without an increase in CO2, as determined by arterial blood gas analysis. Patients in the success group had significantly longer survival (p < 0.001), as determined by the Kaplan-Meier analysis, less need for intubation (p < 0.001), fewer days of hospitalization, and a lower incidence of acute kidney injury in comparison with those in the failure group. Conclusions: The significant improvement in oxygenation parameters, the longer survival, as reflected by the reduced need for intubation and by the mortality rate, and the absence of acute kidney injury suggest that the ELMO CPAP system is a promising tool for treating ARDS and similar clinical conditions.\",\"PeriodicalId\":14845,\"journal\":{\"name\":\"Jornal Brasileiro De Pneumologia\",\"volume\":\"46 2\",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2023-12-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jornal Brasileiro De Pneumologia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.36416/1806-3756/e20230227\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jornal Brasileiro De Pneumologia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.36416/1806-3756/e20230227","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
ELMO CPAP: an innovative type of ventilatory support for COVID-19-related acute respiratory distress syndrome
Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is a retrospective study of 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected on ICU admission, as well as before, during, and after ELMO use. Patients were divided into two groups (success and failure) according to the outcome. Results: ELMO use improved oxygenation parameters such as Pao2, Fio2, and the Pao2/Fio2 ratio, and this contributed to a gradual reduction in Fio2, without an increase in CO2, as determined by arterial blood gas analysis. Patients in the success group had significantly longer survival (p < 0.001), as determined by the Kaplan-Meier analysis, less need for intubation (p < 0.001), fewer days of hospitalization, and a lower incidence of acute kidney injury in comparison with those in the failure group. Conclusions: The significant improvement in oxygenation parameters, the longer survival, as reflected by the reduced need for intubation and by the mortality rate, and the absence of acute kidney injury suggest that the ELMO CPAP system is a promising tool for treating ARDS and similar clinical conditions.
期刊介绍:
The Brazilian Journal of Pulmonology publishes scientific articles that contribute to the improvement of knowledge in the field of the lung diseases and related areas.