罗勒叶提取物对除臭喷雾中金黄色葡萄球菌和表皮葡萄球菌的抗菌活性

T. N. Khairani, Khairani Fitri, Muhammad Andry, Muhammad Amin Nasution
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引用次数: 0

摘要

体臭是一个重要问题,一些体臭过重的人经常会遇到这个问题。罗勒叶(Ocimum Basilicum L.)提取物制成的除臭喷雾剂是一种用于治疗由金黄色葡萄球菌和表皮葡萄球菌引起的体臭的产品。本研究的目的是评估除臭喷雾和罗勒叶提取物对细菌活性的功效,以及除臭喷雾降低这些细菌活性的最佳剂量。研究采用实验方法,使用琼脂扩散法测试抗菌活性。除臭喷雾剂制剂试验结果表明,该制剂均匀,呈有机棕色,有独特的气味,质地为液体;pH 值试验结果符合除臭喷雾剂 4.5-6.5 的要求。各制剂产生的抑菌区平均直径分别为表皮葡萄球菌,阳性对照7 mm,阴性对照10.1 mm;配方5% 12.3 mm;配方10% 13.3 mm;配方15% 12.7 mm抑菌浓度最大的是配方10%为13.3 mm,而金黄色葡萄球菌阳性对照13 mm,阴性对照11.2 mm,5%配方13.1 mm;10%配方13.4 mm;15%配方13.9 mm最大抑菌浓度为15%配方13.9 mm。根据 10%罗勒叶乙醇提取物产生的抑菌区,表皮葡萄球菌的清洁区为 13.3 毫米,金黄色葡萄球菌的清洁区为 26.5 毫米。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The purpose of this study is to assess the efficacy of deodorant spray and basil leaf extract on bacterial activity, as well as the optimal dose of deodorant spray for lowering the activity of these bacteria. Method the research was conducted experimentally, testing antibacterial activity using agar diffusion. The results of the deodorant spray preparation test showed that the preparation was homogeneous, organoleptically brown in color, had a distinctive smell, and had a liquid texture; the pH test results met the requirements for deodorant spray 4.5-6.5. The average diameter of the inhibition zones produced from each preparation were Staphylococcus epidermidis bacteria, positive control 7 mm, negative control 10.1 mm; formula 5% 12.3 mm; formula 10% 13.3 mm; formula 15% 12.7 mm maximum concentration in inhibiting bacteria is formula 10% by 13.3 mm, while the bacteria Staphylococcus Aureus positive control 13 mm, negative control 11.2 mm, 5% formula 13.1 mm; formula 10% 13.4 mm; 15% formula 13.9 mm maximum concentration in inhibiting bacteria is 15% formula 13.9 mm. Based on the inhibitory zone created by 10% basil leaf ethanol extract, Staphylococcus epidermidis bacteria had a 13.3 mm clean zone and Staphylococcus aureus bacteria had a 26.5 mm clean zone.
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