一个 COVID 胆管病病例和文献综述。

Vishwajit Kode, Joseph Puetz, Abrahim N Razzak, Pinky Jha
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引用次数: 0

摘要

导言:胆管病变会导致胆管发炎,出现 "串珠状 "胆红素升高。这种病通常与原发性硬化性胆管炎有关,但现在也有报道称它是 COVID 后的并发症:病例介绍:一名 65 岁的白人男性因 COVID-19 肺炎导致呼吸衰竭、黄疸和亚急性肾损伤而就诊。根据临床表现和磁共振胆胰造影,他被诊断为 COVID-19 胆管病变。不幸的是,由于大面积难治性消化道出血,他被转入临终关怀:讨论:COVID-19 对多个器官系统均有短期和长期影响。胆管病变是COVID-19的一种罕见并发症。大多数病例会导致严重的肝功能衰竭,需要进行肝移植,这与原发性硬化性胆管炎类似:我们报告此病例是为了提高临床医生的认识,使他们在发现不明原因黄疸和有严重 COVID-19 感染史的患者时考虑 COVID-19 胆管病变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case of COVID Cholangiopathy and Literature Review.

Introduction: With cholangiopathy, the bile ducts become inflamed and have a "beads on string appearance" with elevated bilirubin. It is typically associated with primary sclerosing cholangitis but is now being reported as a post-COVID complication.

Case presentation: A 65-year-old White male presented with resolved respiratory failure from COVID-19 pneumonia, jaundice, and likely subacute kidney injury. He was diagnosed with COVID-19 cholangiopathy due to clinical picture and magnetic resonance cholangiopancreatography imaging. Unfortunately, due to a massive refractory gastrointestinal bleed, he was transitioned to hospice care.

Discussion: COVID-19 has been shown to have both short- and long-term effects on multiple organ systems. Cholangiopathy is a rare complication of COVID-19. Most of these cases result in severe liver failure and require liver transplant, similar to primary sclerosing cholangitis.

Conclusions: We report this case to increase awareness among clinicians to consider COVID-19 cholangiopathy in patients with unexplained jaundice and a history of severe COVID-19 infection.

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