{"title":"用胶原酶-山奈敷料和抗生素联合治疗深层糖尿病足趾溃疡:病例报告","authors":"Salkapuram Sunil Kumar , Karthikeyan Elumalai , Srinivasan Sivannan , Sivaneswari Srinivasan , Santhana Krishnan Ramanujam , Binoy Varghese Cherian","doi":"10.1016/j.jhip.2023.11.006","DOIUrl":null,"url":null,"abstract":"<div><p>A diabetic foot ulcer is defined as the ulceration of tissues brought on by trauma and some peripheral neurological abnormalities, primarily as a result of the bacterial infection. The infection of the toe's surrounding tissue is the primary cause of the infectious diabetic toe ulcer. In this case report, a 58-year-old male patient with a deep foot ulcer was admitted to the emergency ward on October 15, 2022, due to pus discharge at the right big toe of the foot. Antibiotics like Vancomycin 30mg per kg twice per day and Ciprofloxacin 400mg twice per day were suggested, along with enzymatic debridement therapy, which helps stop infections faster. A decrease in wound size and an improvement in overall health showed that the patient's response to the combination therapy was encouraging. The use of collagenase-santyl dressings, along with suitable antibiotics, can play a crucial role in the successful treatment of foot ulcers by facilitating wound healing and preventing complications like cellulitis or osteomyelitis.</p></div>","PeriodicalId":100787,"journal":{"name":"Journal of Holistic Integrative Pharmacy","volume":"4 3","pages":"Pages 256-258"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2707368823001115/pdfft?md5=37e8fda96fece55656e6579e7efbaf63&pid=1-s2.0-S2707368823001115-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Combination treatment of a deep diabetic toe ulcer with collagenase-santyl dressings and antibiotics: A case report\",\"authors\":\"Salkapuram Sunil Kumar , Karthikeyan Elumalai , Srinivasan Sivannan , Sivaneswari Srinivasan , Santhana Krishnan Ramanujam , Binoy Varghese Cherian\",\"doi\":\"10.1016/j.jhip.2023.11.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A diabetic foot ulcer is defined as the ulceration of tissues brought on by trauma and some peripheral neurological abnormalities, primarily as a result of the bacterial infection. The infection of the toe's surrounding tissue is the primary cause of the infectious diabetic toe ulcer. In this case report, a 58-year-old male patient with a deep foot ulcer was admitted to the emergency ward on October 15, 2022, due to pus discharge at the right big toe of the foot. Antibiotics like Vancomycin 30mg per kg twice per day and Ciprofloxacin 400mg twice per day were suggested, along with enzymatic debridement therapy, which helps stop infections faster. A decrease in wound size and an improvement in overall health showed that the patient's response to the combination therapy was encouraging. The use of collagenase-santyl dressings, along with suitable antibiotics, can play a crucial role in the successful treatment of foot ulcers by facilitating wound healing and preventing complications like cellulitis or osteomyelitis.</p></div>\",\"PeriodicalId\":100787,\"journal\":{\"name\":\"Journal of Holistic Integrative Pharmacy\",\"volume\":\"4 3\",\"pages\":\"Pages 256-258\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2707368823001115/pdfft?md5=37e8fda96fece55656e6579e7efbaf63&pid=1-s2.0-S2707368823001115-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Holistic Integrative Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2707368823001115\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Holistic Integrative Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2707368823001115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Combination treatment of a deep diabetic toe ulcer with collagenase-santyl dressings and antibiotics: A case report
A diabetic foot ulcer is defined as the ulceration of tissues brought on by trauma and some peripheral neurological abnormalities, primarily as a result of the bacterial infection. The infection of the toe's surrounding tissue is the primary cause of the infectious diabetic toe ulcer. In this case report, a 58-year-old male patient with a deep foot ulcer was admitted to the emergency ward on October 15, 2022, due to pus discharge at the right big toe of the foot. Antibiotics like Vancomycin 30mg per kg twice per day and Ciprofloxacin 400mg twice per day were suggested, along with enzymatic debridement therapy, which helps stop infections faster. A decrease in wound size and an improvement in overall health showed that the patient's response to the combination therapy was encouraging. The use of collagenase-santyl dressings, along with suitable antibiotics, can play a crucial role in the successful treatment of foot ulcers by facilitating wound healing and preventing complications like cellulitis or osteomyelitis.