由巴雷特食管引发的罕见鹅口疮细胞腺癌：食管中的首个报告病例。

IF 1.7 Q3 PATHOLOGY

Journal of Pathology and Translational Medicine Pub Date : 2024-03-01 Epub Date: 2024-01-08 DOI:10.4132/jptm.2023.12.26

Chi Eun Oh, Sung Eun Kim, Sun-Ju Oh

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引用次数: 0

摘要

鹅口疮细胞腺癌（GCA）是一种罕见而独特的两性肿瘤，由鹅口疮样粘液细胞和神经内分泌细胞组成。据信，它起源于位于隐窝底部的多能干细胞。GCA 主要发生在阑尾，也有少数病例发生在阑尾以外的部位，如结肠直肠、小肠和胃。在本病例报告中，我们介绍了一个独特的病例：一名 64 岁的男性最初根据活检结果被诊断为食管远端神经内分泌癌，但在切除食管后，他又被再次诊断为来自巴雷特食管的 GCA。

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A rare goblet cell adenocarcinoma arising from Barrett's esophagus: the first reported case in the esophagus.

Goblet cell adenocarcinoma (GCA) is a rare and distinctive amphicrine tumor comprised of goblet-like mucinous cells and neuroendocrine cells. It is believed to originate from pluripotent stem cells located at the base of crypts. GCA predominantly arises from the appendix, with a few reported cases in extra-appendiceal locations such as the colorectum, small intestine, and stomach. In this case report, we present a unique instance of a 64-year-old male who initially received a diagnosis of neuroendocrine carcinoma in the distal esophagus based on biopsy but, following resection, was subsequently re-diagnosed with GCA arising from Barrett's esophagus.

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来源期刊

Journal of Pathology and Translational Medicine PATHOLOGY-

CiteScore

5.00

自引率

4.20%

发文量

审稿时长

14 weeks

期刊介绍： The Journal of Pathology and Translational Medicine is an open venue for the rapid publication of major achievements in various fields of pathology, cytopathology, and biomedical and translational research. The Journal aims to share new insights into the molecular and cellular mechanisms of human diseases and to report major advances in both experimental and clinical medicine, with a particular emphasis on translational research. The investigations of human cells and tissues using high-dimensional biology techniques such as genomics and proteomics will be given a high priority. Articles on stem cell biology are also welcome. The categories of manuscript include original articles, review and perspective articles, case studies, brief case reports, and letters to the editor.