小胶质细胞过程的动态取决于星形胶质细胞和突触活动。

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Nagoya Journal of Medical Science Pub Date : 2023-11-01 DOI:10.18999/nagjms.85.4.772

Ako Ikegami, Daisuke Kato, Hiroaki Wake

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引用次数: 0

摘要

小胶质细胞过程勘测脑实质，但在生理条件下，这一过程是否受附近小胶质细胞活动的影响尚不清楚。在这里，我们发现当星形胶质细胞活动和突触前活动促进时，小胶质细胞过程的动态会有所不同。结果显示，小胶质细胞过程的动态与其他脑细胞的活动有关。

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Microglial process dynamics depend on astrocyte and synaptic activity.

Microglial processes survey the brain parenchyma, but it is unknown whether this process is influenced by the cell activity of nearby microglia under physiological conditions. Herein, we showed that microglial process dynamics differ when facilitated by astrocytic activity and pre-synaptic activity. The results revealed distinct microglial process dynamics associated with the activity of other brain cells.

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来源期刊

Nagoya Journal of Medical Science MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal publishes original papers in the areas of medical science and its related fields. Reviews, symposium reports, short communications, notes, case reports, hypothesis papers, medical image at a glance, video and announcements are also accepted. Manuscripts should be in English. It is recommended that an English check of the manuscript by a competent and knowledgeable native speaker be completed before submission.