L I Shvaiko, K D Bazyka, M V Shilenko, P V Olifer, N A Tkachuk
{"title":"切尔诺贝利核电站事故清理工人的慢性呼吸系统疾病与阻塞性睡眠呼吸暂停综合征的合并症。","authors":"L I Shvaiko, K D Bazyka, M V Shilenko, P V Olifer, N A Tkachuk","doi":"10.33145/2304-8336-2023-28-444-453","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of the study was to establish the relationship between functional status of bronchopulmonary system and obstructive sleep apnea in clean-up workers of Chornobyl NPP accident in a remote post-accident period.</p><p><strong>Materials and methods: </strong>We included 58 COPD male patients clean-up workers of Chornobyl NPP accident: 21 with obstructive sleep apnea syndrome (OSA), 37 - without. A complex of functional tests and OSA screening was provided.</p><p><strong>Results: </strong>In clean-up workers of Chornobyl NPP accident with COPD and obstructive sleep apnea in a remote post-accident period apnea-hypopnea index (AHI) negatively correlated with FVC, % of predicted (r = -0.36, p < 0.05), the intrathoracic gas volume (ITGV), % of predicted (r = -0.40, p < 0.05); AHI positively correlated with diffusion lung capacity (DLCO), % of predicted values (r = 0.57, p < 0.05), with the intrathoracic gas volume (ITGV), % of predicted (r = 0.53, p < 0.05), body mass index (r = 0.49, p < 0.05) and age (r = 0.62, p < 0.05).</p><p><strong>Conclusions: </strong>Obstructive sleep apnea was diagnosed in 36.3 % of patients with COPD clean up workers of Chornobyl NPP accident. Screening for OSA in patients with COPD, clean-up workers of Chornobyl NPP accident is a very important clinical task for prognosis and treatment.</p>","PeriodicalId":20491,"journal":{"name":"Problemy radiatsiinoi medytsyny ta radiobiolohii","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"THE COMBINATION OF CHRONIC RESPIRATORY DISEASES WITH OBSTRUCTIVE SLEEP APNOEA SYNDROME IN CLEAN-UP WORKERS OF CHORNOBYL NPP ACCIDENT.\",\"authors\":\"L I Shvaiko, K D Bazyka, M V Shilenko, P V Olifer, N A Tkachuk\",\"doi\":\"10.33145/2304-8336-2023-28-444-453\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The objective of the study was to establish the relationship between functional status of bronchopulmonary system and obstructive sleep apnea in clean-up workers of Chornobyl NPP accident in a remote post-accident period.</p><p><strong>Materials and methods: </strong>We included 58 COPD male patients clean-up workers of Chornobyl NPP accident: 21 with obstructive sleep apnea syndrome (OSA), 37 - without. A complex of functional tests and OSA screening was provided.</p><p><strong>Results: </strong>In clean-up workers of Chornobyl NPP accident with COPD and obstructive sleep apnea in a remote post-accident period apnea-hypopnea index (AHI) negatively correlated with FVC, % of predicted (r = -0.36, p < 0.05), the intrathoracic gas volume (ITGV), % of predicted (r = -0.40, p < 0.05); AHI positively correlated with diffusion lung capacity (DLCO), % of predicted values (r = 0.57, p < 0.05), with the intrathoracic gas volume (ITGV), % of predicted (r = 0.53, p < 0.05), body mass index (r = 0.49, p < 0.05) and age (r = 0.62, p < 0.05).</p><p><strong>Conclusions: </strong>Obstructive sleep apnea was diagnosed in 36.3 % of patients with COPD clean up workers of Chornobyl NPP accident. Screening for OSA in patients with COPD, clean-up workers of Chornobyl NPP accident is a very important clinical task for prognosis and treatment.</p>\",\"PeriodicalId\":20491,\"journal\":{\"name\":\"Problemy radiatsiinoi medytsyny ta radiobiolohii\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Problemy radiatsiinoi medytsyny ta radiobiolohii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33145/2304-8336-2023-28-444-453\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Problemy radiatsiinoi medytsyny ta radiobiolohii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33145/2304-8336-2023-28-444-453","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本研究旨在确定切尔诺贝利核电站事故清理工人在事故后远期支气管肺系统功能状态与阻塞性睡眠呼吸暂停之间的关系：我们纳入了58名患有慢性阻塞性肺疾病的切尔诺贝利核电站事故清理工人：21名患有阻塞性睡眠呼吸暂停综合征（OSA），37名没有。结果：切尔诺贝利核电站事故的清洁工人中，有 21 人患有阻塞性睡眠呼吸暂停综合症（OSA），37 人没有：结果：在切尔诺贝利核电站事故清理工人中，有慢性阻塞性肺病和阻塞性睡眠呼吸暂停症状的人在事故后较长时间内的呼吸暂停-低通气指数（AHI）与预测值百分比的肺活量（FVC）呈负相关（r = -0.36，p < 0.05），预测值百分比的胸内气体容积（ITGV）与预测值百分比的呼吸暂停-低通气指数（AHI）呈负相关（r = -0.40，p < 0.05）。40, p < 0.05）；AHI 与弥散肺活量（DLCO）、预测值的百分比（r = 0.57, p < 0.05）、胸腔内气体容积（ITGV）、预测值的百分比（r = 0.53, p < 0.05）、体重指数（r = 0.49, p < 0.05）和年龄（r = 0.62, p < 0.05）呈正相关：切尔诺贝利核电站事故清理工人中有 36.3% 的慢性阻塞性肺疾病患者被诊断出患有阻塞性睡眠呼吸暂停。对切尔诺贝利核电站事故清理工人中的慢性阻塞性肺疾病患者进行 OSA 筛查是一项非常重要的临床工作，有助于预后和治疗。
THE COMBINATION OF CHRONIC RESPIRATORY DISEASES WITH OBSTRUCTIVE SLEEP APNOEA SYNDROME IN CLEAN-UP WORKERS OF CHORNOBYL NPP ACCIDENT.
The objective of the study was to establish the relationship between functional status of bronchopulmonary system and obstructive sleep apnea in clean-up workers of Chornobyl NPP accident in a remote post-accident period.
Materials and methods: We included 58 COPD male patients clean-up workers of Chornobyl NPP accident: 21 with obstructive sleep apnea syndrome (OSA), 37 - without. A complex of functional tests and OSA screening was provided.
Results: In clean-up workers of Chornobyl NPP accident with COPD and obstructive sleep apnea in a remote post-accident period apnea-hypopnea index (AHI) negatively correlated with FVC, % of predicted (r = -0.36, p < 0.05), the intrathoracic gas volume (ITGV), % of predicted (r = -0.40, p < 0.05); AHI positively correlated with diffusion lung capacity (DLCO), % of predicted values (r = 0.57, p < 0.05), with the intrathoracic gas volume (ITGV), % of predicted (r = 0.53, p < 0.05), body mass index (r = 0.49, p < 0.05) and age (r = 0.62, p < 0.05).
Conclusions: Obstructive sleep apnea was diagnosed in 36.3 % of patients with COPD clean up workers of Chornobyl NPP accident. Screening for OSA in patients with COPD, clean-up workers of Chornobyl NPP accident is a very important clinical task for prognosis and treatment.
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