电离辐射对乳腺癌发病的影响。

D A Bazyka, O O Lytvynenko, O O Litvinenko
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引用次数: 0

摘要

乳腺癌(BC)是医疗保健领域亟待解决的问题之一,且呈持续增长趋势。电离辐射(IR)是乳腺癌发病的危险因素之一。大量流行病学和实验研究表明,乳腺(MG)对这一因素高度敏感。对受辐照者发生放射性诱导的乳腺肿瘤的绝对风险和相对风险模型的研究表明,辐照时的年龄、多重性、辐照频率、剂量水平以及乳腺和甲状腺(TG)伴随的非肿瘤性疾病等因素非常重要。广岛和长崎原子弹爆炸后,在接受辐照的妇女中发现了过多由辐射诱发的宫颈癌病例。由于 MG 对红外线的致癌作用非常敏感,这种形式的肿瘤在切尔诺贝利事故后引起了特别关注。切尔诺贝利灾难后,小剂量辐射的影响导致乳腺癌的发病率在一年中的某些时期呈波浪式变化,辐射诱发的这种病变的发病率可能会自发发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
INFLUENCE OF IONIZING RADIATION ON THE DEVELOPMENT OF BREAST CANCER.

Breast cancer (BC) is one of the urgent problems of health care, which is due to a constant trend of growth. One of the risk factors for the development of breast cancer is ionizing radiation (IR). Numerous epidemiological and experimental studies have shown the high sensitivity of the mammary gland (MG) to this factor. Consideration of models of absolute and relative risks of the occurrence of radio-induced tumors of the MG in irradiated persons showed the importance of such factors as age at the time of irradiation, multiplicity. frequency of exposure, dose level and concomitant non-neoplastic diseases of the mammary and thyroid gland (TG). Excess radiation-induced cases of cervical cancer were found among irradiated women after the atomic bombings of Hiroshima and Nagasaki.Epidemiological features of the development of breast cancer under the influence of IV are presented in detail, which is one of the environmental factors involved in the formation of the modern carcinogenic situation. In con-nection with the significant sensitivity of the MG to the carcinogenic effect of IR, this form of neoplasms attracted special attention after the Chornobyl accident. The effect of small doses of radiation after the Chornobyl disaster led to a wave-like change in the incidence of breast cancer in certain periods of the year, and the radiation-induced incidence of this pathology can occur spontaneously.

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Problemy radiatsiinoi medytsyny ta radiobiolohii
Problemy radiatsiinoi medytsyny ta radiobiolohii Medicine-Radiology, Nuclear Medicine and Imaging
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