依托泊苷、泼尼松龙、长春新碱和环磷酰胺治疗皮肤淋巴瘤方案中的舌头和牙齿色素沉着症

IF 1.4 4区医学 Q4 PHARMACOLOGY & PHARMACY

Indian Journal of Pharmacology Pub Date : 2023-12-27 DOI:10.4103/ijp.ijp_53_23

Soumya Shivalingappa Morabad, Zahed Ullah Khan, Richa Gad, Nikitha Kallur, Irappa Vithoba Madhabhavi, Mallappa Hanumanthappa Shalavadi, Chandrashekhar Venkaraddi Mangannavar

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引用次数: 0

摘要

皮肤结节外非霍奇金淋巴瘤是一种罕见的癌症，依托泊苷、长春新碱和环磷酰胺等化疗药物是首选药物，很少引起皮肤和指甲的色素沉着。然而，我们在此介绍了一例色素沉着病例，患者的舌头甚至牙齿都出现了色素沉着。舌头和牙齿的色素沉着发生在化疗开始后不久。色素沉着是自限性的，一周后即可痊愈，无需任何药物、手术或生活方式干预。

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Tongue and teeth hyperpigmentation in etoposide, prednisolone, vincristine, and cyclophosphamide regimen in the treatment of cutaneous lymphoma

Cutaneous extranodal non-Hodgkin lymphoma is a rare cancer and chemotherapeutic agents like etoposide, vincristine and cyclophosphamide are the drug of choice, which rarely cause hyperpigmentation in skin and nails. However, herein we present a case of hyperpigmentation that was seen in tongue and even in teeth. The hyperpigmentation of the tongue and teeth occurred shortly after the initiation of chemotherapy. Hyperpigmentation was self-limiting and rectified in a week without need of any pharmacological, surgical, or lifestyle interventions.

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来源期刊

Indian Journal of Pharmacology 医学-药学

CiteScore

4.00

自引率

4.20%

发文量

审稿时长

4-8 weeks

期刊介绍： Indian Journal of Pharmacology accepts, in English, review articles, articles for educational forum, original research articles (full length and short communications), letter to editor, case reports and interesting fillers. Articles concerning all aspects of pharmacology will be considered. Articles of general interest (e.g. methods, therapeutics, medical education, interesting websites, new drug information and commentary on a recent topic) are also welcome.