不同类型心力衰竭急性缺血性脑卒中患者的特征和预后比较

IF 1.2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
International heart journal Pub Date : 2024-01-31 Epub Date: 2023-12-27 DOI:10.1536/ihj.22-717
Jiongxing Wu, Mingxi Chen, Huan Wang, Yuyi Zhu, Yaqi Chen, Shihong Zhang, Deren Wang
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引用次数: 0

摘要

急性缺血性卒中(AIS)可并发射血分数保留型心力衰竭(HFpEF)或射血分数降低型心力衰竭(HFrEF),这两种类型患者的预后是否存在差异仍不清楚。我们对 2018 年 1 月 1 日至 2021 年 1 月 1 日期间因 HFrEF 或 HFpEF 而并发 AIS 的患者进行了回顾性分析。所有患者均已在成都卒中登记中心进行了前瞻性登记。不良预后定义为3个月时改良Rankin量表(mRS)评分为2-6分。在最终的108名患者样本中(60.2%为男性,平均年龄(73.08 ± 10.82)岁),75人(69.4%)患有HFpEF。与 HFrEF 患者相比,HFpEF 患者年龄更大(P = 0.002),更有可能患有慢性肾病(P = 0.033),更有可能出现不良预后(P = 0.022)。经调整后,HFpEF与不良预后风险显著高于HFrEF相关(OR 4.13,95%CI 1.20-15.79,P = 0.029)。然而,两种类型的心衰在 AIS 后 3 个月的出血转化率或死亡率并无显著差异(P 均 > 0.05)。AIS 合并 HFpEF 患者的预后比 HFrEF 患者更差,因此可能需要特殊的监测和管理。我们的研究结果需要在大型前瞻性研究中得到验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Characteristics and Outcomes Between Acute Ischemic Stroke Patients with Different Types of Heart Failure.

Acute ischemic stroke (AIS) can be complicated by heart failure involving preserved ejection fraction (HFpEF) or reduced ejection fraction (HFrEF), and whether or not the prognosis differs between the 2 types of patients remains unclear. We compared the clinical characteristics and outcomes of the 2 types of patients at 3 months after the stroke.We retrospectively analyzed patients who, between 1 January 2018 and 1 January 2021, experienced AIS that was complicated by HFrEF or HFpEF. All patients had been prospectively registered in the Chengdu Stroke Registry. Poor outcome was defined as a modified Rankin Scale (mRS) score of 2-6 at 3 months. Univariate and binary logistic regression was used to assess whether HFpEF was associated with a significantly worse prognosis than HFrEF.Among the final sample of 108 patients (60.2% men; mean age, 73.08 ± 10.82 years), 75 (69.4%) had HFpEF. Compared to HFrEF patients, those with HFpEF were older (P = 0.002), were more likely to have chronic kidney disease (P = 0.033), and were more likely to experience a poor outcome (P = 0.022). After adjustments, HFpEF was associated with significantly greater risk of poor outcome than HFrEF (OR 4.13, 95%CI 1.20-15.79, P = 0.029). However, rates of hemorrhagic transformation or mortality at 3 months after AIS did not differ significantly between the 2 types of heart failure (all P > 0.05).Patients with AIS involving HFpEF experience worse outcomes than those with HFrEF and therefore may require special monitoring and management. Our findings need to be verified in large prospective studies.

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来源期刊
International heart journal
International heart journal 医学-心血管系统
CiteScore
2.50
自引率
6.70%
发文量
148
审稿时长
6-12 weeks
期刊介绍: Authors of research articles should disclose at the time of submission any financial arrangement they may have with a company whose product figures prominently in the submitted manuscript or with a company making a competing product. Such information will be held in confidence while the paper is under review and will not influence the editorial decision, but if the article is accepted for publication, the editors will usually discuss with the authors the manner in which such information is to be communicated to the reader.
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