开发用于外部应用的喷雾技术基础

M. Dronik, I. Jonuškienė, M. V. Stasevych
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引用次数: 0

摘要

开发了具有镇痛和消炎作用的外用喷雾制剂的基本制备技术。提出了活性药物成分和辅料的定量含量。对获得的喷雾剂的一些指标与乌克兰医药市场上的同类产品进行了比较分析。通过材料计算,可以估算出在实验室中制备喷雾剂并用滴管装瓶所需的活性药物成分和辅料的用量。在材料计算的基础上,提出了生产成品的基本技术方案。进行的经济计算表明,开发这种制剂具有很高的经济效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DEVELOPMENT OF THE BASICS OF SPRAY TECHNOLOGY FOR EXTERNAL APPLICATION
The basics of the technology for the preparation of a spray formulation for external use with analgesic and anti-inflammatory effects was developed. The quantitative content of active pharmaceutical ingredients and excipients was proposed. Comparative analysis of some indicators of the obtained spray with analogues on the pharmaceutical market of Ukraine was carried out. Material calculations allowed to estimate the amount of active pharmaceutical ingredients and excipients for the preparation of the spray and its packaging in bottles with a dropper in the laboratory. Based on the material calculations, a basic technological scheme for the production of the finished product was proposed. Economic calculations have been carried out, which demonstrate a high level of economic profitability of the development of such a preparation.
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