类风湿性关节炎急性加重的致命病例--COVID 疫苗诱发的相关间质性肺病

IF 0.8 Q4 RESPIRATORY SYSTEM

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI:10.1016/j.rmcr.2023.101959

Rayan Mohamad, Rami Hallak, Imad Bou Akl, Hisham Bou Fakhreddine

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引用次数: 0

摘要

间质性肺病（ILD）加重是一种严重的疾病，发病率和死亡率都很高。确定 ILD 加重的诱因非常具有挑战性。一些病例报告描述了 COVID-19 疫苗诱发的潜在间质性肺病（即特发性间质性肺炎）加重。人们对这种不良反应的临床影响认识不足。我们报告了一例类风湿性关节炎间质性肺病患者在接种第二剂 COVID 疫苗几天后出现致命性呼吸衰竭的病例。识别这种并发症的风险因素对于帮助快速识别和及早开始治疗至关重要。

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A Lethal Case of Acute Exacerbation of Rheumatoid Arthritis – Related Interstitial Lung Disease Induced by the COVID Vaccine.

Interstitial lung disease (ILD) exacerbation is a serious condition that can have a high morbidity and mortality. Identifying the triggers of ILD exacerbations is very challenging. Several case reports described COVID-19 vaccine-induced exacerbation of underlying interstitial lung disease, namely idiopathic interstitial pneumonias. The clinical implications of this adverse effect is underrecognized. We are reporting a case of fatal respiratory failure in a patient with rheumatoid arthritis Interstitial Lung disease few days following the second dose of COVID vaccine. Identifying risk factors of this complication is of utmost importance to aid in the rapid recognition and early initiation of treatment.

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