妊娠期牙周病概述

Mohammed Ibrahim Aloqayfi, Yahya Nasser Alayed, Manal Abdullah Alshareef, Amany Sami Alfawzan, Azhar Hussain Asiry, Nourah Nasser Almalik, Afnan Faisal Almalki, Ali Abdullah Alharbi, Bassem Othman Alomari
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摘要

牙周病(PD)是一种影响牙齿支撑组织的炎症和感染性疾病,由于荷尔蒙的变化,这种疾病在孕妇中很普遍。研究表明,牙周病与不良妊娠结局(包括早产和新生儿体重过轻)之间存在联系,这可能是由于炎症介质增加所致。连翘丹那菌和牙龈卟啉单胞菌等口腔病原体与这些并发症有关。影响孕妇妊娠过程的最常见口腔疾病是牙周炎、牙龈炎和龋齿。从龈上斑块到龈下感染和龋齿,这些病症相互关联。母体血清中这些病原体抗体和炎症标志物的升高与不良妊娠结局相关。动物模型进一步证实了牙周病与胎儿健康问题之间的联系。虽然研究表明牙周治疗可以降低风险,但确切的机制仍然是复杂和多因素的。将牙科保健纳入产前保健对于预防和管理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An overview of periodontal disease in pregnancy
Periodontal disease (PD), an inflammatory and infectious condition affecting the tissues supporting teeth, is prevalent among pregnant women due to hormonal changes. Studies indicate a link between PD and adverse pregnancy outcomes, including preterm labor and low birthweight newborns, likely due to increased inflammatory mediators. Oral pathogens like Tannerella forsythia and Porphyromonas gingivalis have been associated with these complications. The most prevalent oral conditions affecting pregnant women that may influence the course of their pregnancy are periodontitis, gingivitis, and dental caries. From supragingival plaques to subgingival infections and PD, these conditions are linked to one another. Elevated maternal serum antibodies to these pathogens and inflammatory markers correlate with poor pregnancy outcomes. Animal models further support the connection between PD and fetal health issues. While research suggests that periodontal treatment may reduce the risk, the exact mechanisms remain complex and multifactorial. Integrating dental care into prenatal care is vital for prevention and management.  
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