小儿急性淋巴细胞白血病患者天冬酰胺酶相关性胰腺炎并发胰液收集,采用内镜下胰腺造瘘术治疗:病例报告与文献系统回顾》。

Giulia Fiumana, Alessia Pancaldi, Helga Bertani, Valentina Boarino, Monica Cellini, Lorenzo Iughetti
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引用次数: 0

摘要

在接受急性淋巴细胞白血病治疗的患者中,2%-10%的患者会并发天冬酰胺酶相关性胰腺炎,导致发病和停止天冬酰胺酶用药。在急性并发症中,胰液积聚可采取保守治疗,但如果伴有持续的胰岛素治疗需求和反复腹痛,则需要进行干预。内镜治疗已成为成人患者的标准方法,在儿童患者中也有越来越多的有利证据。本研究将本院治疗的一名儿科肿瘤患者的特征与文献报道的经验进行了比较,显示了内镜方法的可行性、安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Asparaginase-associated Pancreatitis Complicated by Pancreatic Fluid Collection Treated with Endoscopic Cistogastrostomy in Pediatric Acute Lymphoblastic Leukemia: A Case Report and Systematic Review of the Literature.
Asparaginase-associated pancreatitis complicates 2-10% of patients treated for acute lymphoblastic leukemia, causing morbidity and discontinuation of asparaginase administration. Among acute complications, pancreatic fluid collections can be managed conservatively, but intervention is indicated when associated with persistent insulin therapy need and recurrent abdominal pain. Endoscopic treatment has become the standard approach in adult patients, with increasing favorable evidence in children. This work compares the characteristics of a pediatric oncology patient treated at our institution with reported literature experiences, showing feasibility, safety and effectiveness of endoscopic approach.
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